IMR OpenIR
Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines
Alternative TitleOrganocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines
Yu Fang1; Zhang Xiaojing1; Jiang Yongwen2
2011
Source PublicationCHINESE JOURNAL OF CHEMISTRY
ISSN1001-604X
Volume29Issue:9Pages:1873-1879
AbstractA convenient and highly enantioselective method for assembly of functionalized 1,2,3,4,5-pentasubstituted tetrahydropyridines and piperidines was developed. This method relies on preparing the required enantiopure cyclic semi-acetals via an organocatalyzed Michael addition/cyclization cascade reaction of aldehydes and alpha-keto-alpha,beta-unsaturated esters, and subsequent reductive amination/condensation with primary amines.
Other AbstractA convenient and highly enantioselective method for assembly of functionalized 1,2,3,4,5-pentasubstituted tetrahydropyridines and piperidines was developed. This method relies on preparing the required enantiopure cyclic semi-acetals via an organocatalyzed Michael addition/cyclization cascade reaction of aldehydes and α-keto-α,β-unsaturated esters, and subsequent reductive amination/condensation with primary amines.
KeywordMICHAEL ADDITION 2,4-DISUBSTITUTED PIPERIDINES MULTICOMPONENT REACTIONS ALDEHYDES CYCLIZATION SCAFFOLDS ENTRY WATER organocatalysis Michael addition reductive amination substituted piperidine tetrahydropyridine
Indexed ByCSCD
Language英语
Funding Project[National Natural Science Foundation of China]
CSCD IDCSCD:4352577
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/146210
Collection中国科学院金属研究所
Affiliation1.中国科学院金属研究所
2.中国科学院
Recommended Citation
GB/T 7714
Yu Fang,Zhang Xiaojing,Jiang Yongwen. Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines[J]. CHINESE JOURNAL OF CHEMISTRY,2011,29(9):1873-1879.
APA Yu Fang,Zhang Xiaojing,&Jiang Yongwen.(2011).Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines.CHINESE JOURNAL OF CHEMISTRY,29(9),1873-1879.
MLA Yu Fang,et al."Organocatalytically Enantioselective Approach to Polysubstituted Tetrahydropyridines and Piperidines".CHINESE JOURNAL OF CHEMISTRY 29.9(2011):1873-1879.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yu Fang]'s Articles
[Zhang Xiaojing]'s Articles
[Jiang Yongwen]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yu Fang]'s Articles
[Zhang Xiaojing]'s Articles
[Jiang Yongwen]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yu Fang]'s Articles
[Zhang Xiaojing]'s Articles
[Jiang Yongwen]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.