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Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population
Alternative TitleCorrelation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population
Liu YanJie; Wang XiaoZeng; Wang Ya; He RuiXia; Yang Lin; Jing QuanMin; Liu HaiWei
2018
Source PublicationChinese Medical Journal
ISSN0366-6999
Volume131Issue:12Pages:1430-1435
AbstractBackground: The prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex. Greater understanding on the differences between men and women with acute aortic dissection (AAD) is needed. We aimed to investigate whether sex disparities are found in patients with AAD, and to study sex differences in complications, mortality in-hospital, and long-term. Methods: We included 884 patients enrolled in our institute between June 2002 and May 2016. Considering psychosocial factors, treatments, and the outcomes in men versus those in women with AAD, we explored the association of sex with psychosocial characteristics and mortality risk. For categorical variables, significant differences between groups were assessed with the Chi-square test or Fisher's exact test, and continuous parameters were assessed with Student's t-test. Univariate and stratified survival statistics were computed using Kaplan-Meier analysis. Results: A total of 884 patients (76.1% male, mean age 51.4 ± 11.8 years) were included in this study. There were fewer current smokers in female compared with male (17.5% vs. 67.2%, χ2 = 160.06, P < 0.05). The percentage of men who reported regular alcohol consumption was significantly higher than that in women (40.6% vs. 3.8%, χ2 = 100.18, P < 0.05). About 6.2% (55 of 884) of patients with AAD died before vascular or endovascular surgery was performed, 34.4% (304 of 884) of patients underwent surgical procedures, and 52.7% (466 of 884) and 12.8% (113 of 884) of patients received endovascular treatment and medication. Postoperative mortality similar (6.0% vs. 5.6%, respectively, χ2 = 0.03, P = 0.91) between men and women. Follow-up was completed in 653 of 829 patients (78.8%). Adjustment for age, history of coronary disease, hypertension, smoking and drinking, Type A and use of beta-blocker, angiotensin II receptor blockers, angiotensin converting enzyme (ACE) inhibitor, calcium-channel blockers and statins by multivariate logistic regression analysis suggested that age (odds ratios OR s
Other AbstractBackground: The prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex. Greater understanding on the differences between men and women with acute aortic dissection (AAD) is needed. We aimed to investigate whether sex disparities are found in patients with AAD, and to study sex differences in complications, mortality in-hospital, and long-term. Methods: We included 884 patients enrolled in our institute between June 2002 and May 2016. Considering psychosocial factors, treatments, and the outcomes in men versus those in women with AAD, we explored the association of sex with psychosocial characteristics and mortality risk. For categorical variables, significant differences between groups were assessed with the Chi-square test or Fisher's exact test, and continuous parameters were assessed with Student's t-test. Univariate and stratified survival statistics were computed using Kaplan-Meier analysis. Results: A total of 884 patients (76.1 % male, mean age 51.4 ± 11.8 years) were included in this study. There were fewer current smokers in female compared with male (17.5% vs. 67.2%, χ~2 = 160.06,P < 0.05). The percentage of men who reported regular alcohol consumption was significantly higher than that in women (40.6% vs. 3.8%,χ~2 = 100.18,P< 0.05). About 6.2% (55 of 884) of patients with AAD died before vascular or endovascular surgery was performed, 34.4% (304 of 884) of patients underwent surgical procedures, and 52.7% (466 of 884) and 12.8% (113 of 884) of patients received endovascular treatment and medication. Postoperative mortality similar (6.0% vs. 5.6%, respectively, χ~2 = 0.03,P = 0.91) between men and women. Follow-up was completed in 653 of 829 patients (78.8%). Adjustment for age, history of coronary disease, hypertension, smoking and drinking, Type A and use of beta-blocker, angiotensin II receptor blockers, angiotensin converting enzyme (ACE) inhibitor, calcium-channel blockers and statins by multivariate logistic regression analysis suggested that age (odds ratios ORs
KeywordAortic Dissection Medicine R Prognosis Sex
Indexed ByCSCD
Language英语
Funding Project[National Key Project of Research and Development Plan during the Thirteenth Five-year Plan Period] ; [Construction Program of National Clinical Priority Speciality]
CSCD IDCSCD:6266042
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/146329
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Liu YanJie,Wang XiaoZeng,Wang Ya,et al. Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population[J]. Chinese Medical Journal,2018,131(12):1430-1435.
APA Liu YanJie.,Wang XiaoZeng.,Wang Ya.,He RuiXia.,Yang Lin.,...&Liu HaiWei.(2018).Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population.Chinese Medical Journal,131(12),1430-1435.
MLA Liu YanJie,et al."Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population".Chinese Medical Journal 131.12(2018):1430-1435.
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