Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population

IMR OpenIR

	Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population
其他题名	Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population
	Liu YanJie; Wang XiaoZeng; Wang Ya; He RuiXia; Yang Lin; Jing QuanMin; Liu HaiWei
	2018
发表期刊	Chinese Medical Journal
ISSN	0366-6999
卷号	131 期号:12 页码:1430-1435
摘要	Background: The prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex. Greater understanding on the differences between men and women with acute aortic dissection (AAD) is needed. We aimed to investigate whether sex disparities are found in patients with AAD, and to study sex differences in complications, mortality in-hospital, and long-term. Methods: We included 884 patients enrolled in our institute between June 2002 and May 2016. Considering psychosocial factors, treatments, and the outcomes in men versus those in women with AAD, we explored the association of sex with psychosocial characteristics and mortality risk. For categorical variables, significant differences between groups were assessed with the Chi-square test or Fisher's exact test, and continuous parameters were assessed with Student's t-test. Univariate and stratified survival statistics were computed using Kaplan-Meier analysis. Results: A total of 884 patients (76.1% male, mean age 51.4 ± 11.8 years) were included in this study. There were fewer current smokers in female compared with male (17.5% vs. 67.2%, χ2 = 160.06, P < 0.05). The percentage of men who reported regular alcohol consumption was significantly higher than that in women (40.6% vs. 3.8%, χ2 = 100.18, P < 0.05). About 6.2% (55 of 884) of patients with AAD died before vascular or endovascular surgery was performed, 34.4% (304 of 884) of patients underwent surgical procedures, and 52.7% (466 of 884) and 12.8% (113 of 884) of patients received endovascular treatment and medication. Postoperative mortality similar (6.0% vs. 5.6%, respectively, χ2 = 0.03, P = 0.91) between men and women. Follow-up was completed in 653 of 829 patients (78.8%). Adjustment for age, history of coronary disease, hypertension, smoking and drinking, Type A and use of beta-blocker, angiotensin II receptor blockers, angiotensin converting enzyme (ACE) inhibitor, calcium-channel blockers and statins by multivariate logistic regression analysis suggested that age (odds ratios OR s
其他摘要	Background: The prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex. Greater understanding on the differences between men and women with acute aortic dissection (AAD) is needed. We aimed to investigate whether sex disparities are found in patients with AAD, and to study sex differences in complications, mortality in-hospital, and long-term. Methods: We included 884 patients enrolled in our institute between June 2002 and May 2016. Considering psychosocial factors, treatments, and the outcomes in men versus those in women with AAD, we explored the association of sex with psychosocial characteristics and mortality risk. For categorical variables, significant differences between groups were assessed with the Chi-square test or Fisher's exact test, and continuous parameters were assessed with Student's t-test. Univariate and stratified survival statistics were computed using Kaplan-Meier analysis. Results: A total of 884 patients (76.1 % male, mean age 51.4 ± 11.8 years) were included in this study. There were fewer current smokers in female compared with male (17.5% vs. 67.2%, χ~2 = 160.06,P < 0.05). The percentage of men who reported regular alcohol consumption was significantly higher than that in women (40.6% vs. 3.8%,χ~2 = 100.18,P< 0.05). About 6.2% (55 of 884) of patients with AAD died before vascular or endovascular surgery was performed, 34.4% (304 of 884) of patients underwent surgical procedures, and 52.7% (466 of 884) and 12.8% (113 of 884) of patients received endovascular treatment and medication. Postoperative mortality similar (6.0% vs. 5.6%, respectively, χ~2 = 0.03,P = 0.91) between men and women. Follow-up was completed in 653 of 829 patients (78.8%). Adjustment for age, history of coronary disease, hypertension, smoking and drinking, Type A and use of beta-blocker, angiotensin II receptor blockers, angiotensin converting enzyme (ACE) inhibitor, calcium-channel blockers and statins by multivariate logistic regression analysis suggested that age (odds ratios ORs
关键词	Aortic Dissection Medicine R Prognosis Sex
收录类别	CSCD
语种	英语
资助项目	[National Key Project of Research and Development Plan during the Thirteenth Five-year Plan Period] ; [Construction Program of National Clinical Priority Speciality]
CSCD记录号	CSCD:6266042
引用统计	被引频次：2[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/146329
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Liu YanJie,Wang XiaoZeng,Wang Ya,et al. Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population[J]. Chinese Medical Journal,2018,131(12):1430-1435.
APA	Liu YanJie.,Wang XiaoZeng.,Wang Ya.,He RuiXia.,Yang Lin.,...&Liu HaiWei.(2018).Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population.Chinese Medical Journal,131(12),1430-1435.
MLA	Liu YanJie,et al."Correlation between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population".Chinese Medical Journal 131.12(2018):1430-1435.