Ring-restricted N-nitrosated rhodamine as a green-light triggered, orange-emission calibrated and fast-releasing nitric oxide donor

IMR OpenIR

	Ring-restricted N-nitrosated rhodamine as a green-light triggered, orange-emission calibrated and fast-releasing nitric oxide donor
	He Haihong 1; He Tingting 1; Zhang Ziqian 2; Xu Xiu 1; Yang Huibin 3; Qian Xuhong 4; Yang Youjun 4
	2018
发表期刊	CHINESE CHEMICAL LETTERS
ISSN	1001-8417
卷号	29 期号:10 页码:1497-1499
摘要	Nitric oxide (NO) donors are versatile tools for nitric oxide biology. The biological response of NO is dependent on the transient concentration and the sustained duration. N-Nitrosated rhodamines are photo-triggered and photo-calibrated NO donors. We recently discovered that suppression of the dihedral angle between the N-nitroso fragment with the rhodamine scaffold facilitates NO release. Inspired by this discovery, we developed a fast-releasing NO donor (NOD575) suitable for biological applications, e.g., the pulmonary arterial smooth muscle cells (PASMCs). (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
其他摘要	Nitric oxide (NO) donors are versatile tools for nitric oxide biology. The biological response of NO is dependent on the transient concentration and the sustained duration. N-Nitrosated rhodamines are photo-triggered and photo-calibrated NO donors. We recently discovered that suppression of the dihedral angle between the N-nitroso fragment with the rhodamine scaffold facilitates NO release. Inspired by this discovery, we developed a fast-releasing NO donor (NOD575) suitable for biological applications, e.g., the pulmonary arterial smooth muscle cells (PASMCs).
关键词	MITOCHONDRIAL DYNAMICS PHOTON NO donor Photo-trigger Photo-calibrate Platelet aggregation inhibition Antimicrobial
收录类别	CSCD
语种	英语
资助项目	[National Natural Science Foundation of China] ; [Fundamental Research Funds for the Central Universities]
CSCD记录号	CSCD:6346033
引用统计	被引频次：2[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/147813
专题	中国科学院金属研究所
作者单位	1.陕西省地震局 2.广西大学 3.中国科学院金属研究所 4.East China University Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China
推荐引用方式 GB/T 7714	He Haihong,He Tingting,Zhang Ziqian,et al. Ring-restricted N-nitrosated rhodamine as a green-light triggered, orange-emission calibrated and fast-releasing nitric oxide donor[J]. CHINESE CHEMICAL LETTERS,2018,29(10):1497-1499.
APA	He Haihong.,He Tingting.,Zhang Ziqian.,Xu Xiu.,Yang Huibin.,...&Yang Youjun.(2018).Ring-restricted N-nitrosated rhodamine as a green-light triggered, orange-emission calibrated and fast-releasing nitric oxide donor.CHINESE CHEMICAL LETTERS,29(10),1497-1499.
MLA	He Haihong,et al."Ring-restricted N-nitrosated rhodamine as a green-light triggered, orange-emission calibrated and fast-releasing nitric oxide donor".CHINESE CHEMICAL LETTERS 29.10(2018):1497-1499.