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Comparison of transient changes in renal function between off-pump and on-pump coronary artery bypass grafting
Alternative TitleComparison of transient changes in renal function between off-pump and on-pump coronary artery bypass grafting
Zhang Wenfeng; Gu Tianxiang; Diao Cheng; Zhang Yuhai; Wang Chun; Fang Qin; Wang Hailong
2008
Source PublicationCHINESE MEDICAL JOURNAL
ISSN0366-6999
Volume121Issue:16Pages:1537-1542
AbstractBackground Acute renal failure following coronary artery bypass grafting (CABG) surgery is associated with high morbidity and mortality. Approximately half of all patients who develop acute kidney injury (AKI) subsequently develop acute renal failure (ARF). The purpose of the study was to compare early transient changes in renal function within the first post-operative week following CABG in patients that were either off-pump or on-pump.
Other AbstractBackground Acute renal failure following coronary artery bypass grafting(CABG)surgery is associated with high morbidity and mortality.Approximately half of all patients who develop acute kidney injury(AKI)subsequently develop acute renal failure(ARF).The purpose of the study was to compare early transient changes in renal function within the first post-operative week following CABG in patients that were either off-pump or on-pump.Methods Eight hundred and forty-nine consecutive patients with isolated CABG in a single institution between January 1990 and August 2006 were retrospectively analyzed.including 51 8 off-pump and 331 on-pump patients.A multivariate Logistic regression model was constructed to identify risk factors for the development of AKI.Results sixty-one off-pump patients and 63 on-pump patients developed AKI.Risk factors for the development of post-operative AKI included an ejection fraction≥50%or≤30%,a pulse pressure>60 mmHg,peripheral vascular disease,diabetes,emergent procedure,triple-vessel disease,body mass index,peri-operative and post-operative.intra.aortic balloon pumping,NYHA class III and IV,and cardiopulmonary bypass.An ejection fraction Z50%and peri-operative and post-operative intra-aortic balloon pumping were protective(OR<1).Peak serum creatinine for post-operative Akl was noted 12 hours and 24 hours in the off-pump and on-pump patients,respectively.Serum creatinine kinetics revealed rapid recovery in the 24th to 48th hour(off-pump)and the 48th to 72nd hour(on-pump).Conclusion Renal protection strategies are indicated from general anesthesia induction until 48 and 72 houm post-operatively in off-pump and on-pump patients,respectively.
KeywordCARDIOPULMONARY BYPASS SERUM CREATININE CARDIAC-SURGERY HOSPITAL MORTALITY FAILURE DYSFUNCTION REVASCULARIZATION ASSOCIATION PREDICTION DIALYSIS coronary artery bypass grafts kidney injury risk analysis
Indexed ByCSCD
Language英语
Funding Project[Department of Education of Liaoning Province, China]
CSCD IDCSCD:3431575
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/148839
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Zhang Wenfeng,Gu Tianxiang,Diao Cheng,et al. Comparison of transient changes in renal function between off-pump and on-pump coronary artery bypass grafting[J]. CHINESE MEDICAL JOURNAL,2008,121(16):1537-1542.
APA Zhang Wenfeng.,Gu Tianxiang.,Diao Cheng.,Zhang Yuhai.,Wang Chun.,...&Wang Hailong.(2008).Comparison of transient changes in renal function between off-pump and on-pump coronary artery bypass grafting.CHINESE MEDICAL JOURNAL,121(16),1537-1542.
MLA Zhang Wenfeng,et al."Comparison of transient changes in renal function between off-pump and on-pump coronary artery bypass grafting".CHINESE MEDICAL JOURNAL 121.16(2008):1537-1542.
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