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Incidence and predictors of definite stent thrombosis after coronary stent implantation
Alternative TitleIncidence and predictors of definite stent thrombosis after coronary stent implantation
Zhang Quanyu; Li Yi; Guan Shaoyi; Wang Xiaozeng; Jing Quanmin; Ma YingYan; Wang Geng; Wang Bin; Deng Jie; Han Yaling
2012
Source PublicationCHINESE MEDICAL JOURNAL
ISSN0366-6999
Volume125Issue:9Pages:1547-1551
AbstractBackground Coronary stents are widely used in percutaneous coronary intervention (PCI) procedures. We aimed to explore the incidence, predictors and characteristics of stent thrombosis (ST) after coronary stent implantation in routine clinical practice.
Other AbstractBackground Coronary stents are widely used in percutaneous coronary intervention (PCI) procedures. We aimed to explore the incidence, predictors and characteristics of stent thrombosis (ST) after coronary stent implantation in routine clinical practice. Methods From data of 18 063 consecutive patients who underwent successful stent implantation in Shenyang Northern Hospital from 2004 to 2010, we identified patients with definite ST (n=140) and control patients (n=280) matched on age, diagnosis, sex, current antiplatelet medication and stent type. The incidence, predictors and characteristics of ST after coronary stent implantation were investigated. Results The incidence of angiographically confirmed ST was 0.78% (140/18 063). The time distribution of ST was acute in 43 (30.7%), subacute in 50 (35.7%), and late in 47 (33.6%) patients. Binary Logistic regression analysis identified the angiotensin-converting enzyme inhibitor (ACEI) (odds ratio (OR)=0.472, 95% CI: 0.276–0.807, P=0.006) and heparin (OR=0.477, 95% CI: 0.278–0.819, P=0.007) were associated with an reduced risk of cumulative ST. Stent length (OR=1.042, 95% CI: 1.026–1.058, P <0.001), serum creatinine total (OR=1.020, 95% CI: 1.004–1.035, P=0.04), cholesterol (OR=1.267, 95% CI: 1.021–1.573, P=0.032), glucose (OR=1.086, 95% CI: 1.002–1.176, P=0.044), and platelet aggregation (OR=1.113, 95% CI: 1.075–1.154, P <0.001) were associated with an increased risk of cumulative ST. Conclusion ST is associated with longer stent length and higher level of total cholesterol, glucose and platelet aggregation.
KeywordDRUG-ELUTING STENTS BARE-METAL INTERVENTION TRIAL OUTCOMES ERA stent thrombosis stent implantation myocardial infarction
Indexed ByCSCD
Language英语
CSCD IDCSCD:4523304
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/149490
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Zhang Quanyu,Li Yi,Guan Shaoyi,et al. Incidence and predictors of definite stent thrombosis after coronary stent implantation[J]. CHINESE MEDICAL JOURNAL,2012,125(9):1547-1551.
APA Zhang Quanyu.,Li Yi.,Guan Shaoyi.,Wang Xiaozeng.,Jing Quanmin.,...&Han Yaling.(2012).Incidence and predictors of definite stent thrombosis after coronary stent implantation.CHINESE MEDICAL JOURNAL,125(9),1547-1551.
MLA Zhang Quanyu,et al."Incidence and predictors of definite stent thrombosis after coronary stent implantation".CHINESE MEDICAL JOURNAL 125.9(2012):1547-1551.
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