Incidence and predictors of definite stent thrombosis after coronary stent implantation

IMR OpenIR

	Incidence and predictors of definite stent thrombosis after coronary stent implantation
其他题名	Incidence and predictors of definite stent thrombosis after coronary stent implantation
	Zhang Quanyu; Li Yi; Guan Shaoyi; Wang Xiaozeng; Jing Quanmin; Ma YingYan; Wang Geng; Wang Bin; Deng Jie; Han Yaling
	2012
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
卷号	125 期号:9 页码:1547-1551
摘要	Background Coronary stents are widely used in percutaneous coronary intervention (PCI) procedures. We aimed to explore the incidence, predictors and characteristics of stent thrombosis (ST) after coronary stent implantation in routine clinical practice.
其他摘要	Background Coronary stents are widely used in percutaneous coronary intervention (PCI) procedures. We aimed to explore the incidence, predictors and characteristics of stent thrombosis (ST) after coronary stent implantation in routine clinical practice. Methods From data of 18 063 consecutive patients who underwent successful stent implantation in Shenyang Northern Hospital from 2004 to 2010, we identified patients with definite ST (n=140) and control patients (n=280) matched on age, diagnosis, sex, current antiplatelet medication and stent type. The incidence, predictors and characteristics of ST after coronary stent implantation were investigated. Results The incidence of angiographically confirmed ST was 0.78% (140/18 063). The time distribution of ST was acute in 43 (30.7%), subacute in 50 (35.7%), and late in 47 (33.6%) patients. Binary Logistic regression analysis identified the angiotensin-converting enzyme inhibitor (ACEI) (odds ratio (OR)=0.472, 95% CI: 0.276–0.807, P=0.006) and heparin (OR=0.477, 95% CI: 0.278–0.819, P=0.007) were associated with an reduced risk of cumulative ST. Stent length (OR=1.042, 95% CI: 1.026–1.058, P <0.001), serum creatinine total (OR=1.020, 95% CI: 1.004–1.035, P=0.04), cholesterol (OR=1.267, 95% CI: 1.021–1.573, P=0.032), glucose (OR=1.086, 95% CI: 1.002–1.176, P=0.044), and platelet aggregation (OR=1.113, 95% CI: 1.075–1.154, P <0.001) were associated with an increased risk of cumulative ST. Conclusion ST is associated with longer stent length and higher level of total cholesterol, glucose and platelet aggregation.
关键词	DRUG-ELUTING STENTS BARE-METAL INTERVENTION TRIAL OUTCOMES ERA stent thrombosis stent implantation myocardial infarction
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:4523304
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/149493
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Zhang Quanyu,Li Yi,Guan Shaoyi,et al. Incidence and predictors of definite stent thrombosis after coronary stent implantation[J]. CHINESE MEDICAL JOURNAL,2012,125(9):1547-1551.
APA	Zhang Quanyu.,Li Yi.,Guan Shaoyi.,Wang Xiaozeng.,Jing Quanmin.,...&Han Yaling.(2012).Incidence and predictors of definite stent thrombosis after coronary stent implantation.CHINESE MEDICAL JOURNAL,125(9),1547-1551.
MLA	Zhang Quanyu,et al."Incidence and predictors of definite stent thrombosis after coronary stent implantation".CHINESE MEDICAL JOURNAL 125.9(2012):1547-1551.