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Probiotics and irritable bowel syndrome
Alternative TitleProbiotics and irritable bowel syndrome
Dai Cong; Zheng ChangQing; Jiang Min; Ma XiaoYu; Jiang LiJuan
2013
Source PublicationWORLD JOURNAL OF GASTROENTEROLOGY
ISSN1007-9327
Volume19Issue:36Pages:5973-5980
AbstractIrritable bowel syndrome (IBS) is common gastrointestinal problems. It is characterized by abdominal pain or discomfort, and is associated with changes in stool frequency and/or consistency. The etiopathogenesis of IBS may be multifactorial, as is the pathophysiology, which is attributed to alterations in gastrointestinal motility, visceral hypersensitivity, intestinal microbiota, gut epithelium and immune function, dysfunction of the brain-gut axis or certain psychosocial factors. Current therapeutic strategies are often unsatisfactory. There is now increasing evidence linking alterations in the gastrointestinal microbiota and IBS. Probiotics are living organisms which, when ingested in certain numbers, exert health benefits beyond inherent basic nutrition. Probiotics have numerous positive effects in the gastrointestinal tract. Recently, many studies have suggested that probiotics are effective in the treatment of IBS. The mechanisms of probiotics in IBS are very complex. The purpose of this review is to summarize the evidence and mechanisms for the use of probiotics in the treatment of IBS. (C) 2013 Baishideng. All rights reserved.
Other AbstractIrritable bowel syndrome(IBS)is common gastrointestinal problems.It is characterized by abdominal pain or discomfort,and is associated with changes in stool frequency and/or consistency.The etiopathogenesis of IBS may be multifactorial,as is the pathophysiology,which is attributed to alterations in gastrointestinal motility,visceral hypersensitivity,intestinal microbiota,gut epithelium and immune function,dysfunction of the brain-gut axis or certain psychosocial factors.Current therapeutic strategies are often unsatisfactory.There is now increasing evidence linking alterations in the gastrointestinal microbiota and IBS.Probiotics are living organisms which,when ingested in certain numbers,exert health benefits beyond inherent basic nutrition.Probiotics have numerous positive effects in the gastrointestinal tract.Recently,many studies have suggested that probiotics are effective in the treatment of IBS.The mechanisms of probiotics in IBS are very complex.The purpose of this review is to summarize the evidence and mechanisms for the use of probiotics in the treatment of IBS.
KeywordFECAL MICROBIOTA TRANSPLANTATION FUNCTIONAL GASTROINTESTINAL DISORDERS LACTOBACILLUS-RHAMNOSUS GG POSSIBLE MECHANISMS ULCERATIVE-COLITIS CONTROLLED-TRIAL PRIMARY-CARE FLORA MANAGEMENT BACTERIA Probiotics Irritable bowel syndrome Visceral hypersensitivity Brain-gut axis Immune function
Indexed ByCSCD
Language英语
CSCD IDCSCD:5009747
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/149866
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Dai Cong,Zheng ChangQing,Jiang Min,et al. Probiotics and irritable bowel syndrome[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2013,19(36):5973-5980.
APA Dai Cong,Zheng ChangQing,Jiang Min,Ma XiaoYu,&Jiang LiJuan.(2013).Probiotics and irritable bowel syndrome.WORLD JOURNAL OF GASTROENTEROLOGY,19(36),5973-5980.
MLA Dai Cong,et al."Probiotics and irritable bowel syndrome".WORLD JOURNAL OF GASTROENTEROLOGY 19.36(2013):5973-5980.
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