| Screening and identification of multi-classified components in Liushenwan using multi-dimension high performance liquid chromatography tandem mass spectrometry system | |
| Alternative Title | Screening and Identification of Multi-classified Components in Liushenwan Using Multi-dimension High Performance Liquid Chromatography Tandem Mass Spectrometry System |
| Cao Yang1; Liang QiongLin2; Zhang HongYang2; Wang YiMing2; Bi KaiShun1; Luo GuoAn2 | |
| 2008 | |
| Source Publication | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| ISSN | 0253-3820 |
| Volume | 36Issue:1Pages:39-46 |
| Abstract | A multi-dimension HPLC/MS(MSn) analytical model using a combination of HPLC/TOF-MS and HPLC/Ion Trap MS' was used to systemically screen and identify multi-classified components in a traditional Chinese medicine formula Liushenwan. Benefit from combining the accurate mass measurement of HPLC/TOF-MS to generate elemental compositions and the complementary multilevel structural information provided by HPLC/Ion Trap MS', 25 components in Liushenwan were identified in all, the corresponding standards were used for corroboration. All the components identified were surveyed and classified according to their medicinal materials derivation (Musk (Moschus berezovskii Flerov), bezoar (Bos Taurus domesticus Gmelin) and toad venom ( Bufo gargarizans Cantor)). This study is expected to provide an effective and reliable pattern for comprehensive and systematic characterization of the complex systems. |
| Keyword | TRADITIONAL CHINESE MEDICINE BUFADIENOLIDES LC/MS/MS PLANT multi-dimension high performance liquid chromatography tandem mass spectrometry Liushenwan systemic screening and identification high performance liquid chromatography-time of flight mass spectrometry |
| Indexed By | CSCD |
| Language | 英语 |
| CSCD ID | CSCD:3263981 |
| Citation statistics |
Cited Times:7[CSCD]
[CSCD Record]
|
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/150446 |
| Collection | 中国科学院金属研究所 |
| Affiliation | 1.中国科学院金属研究所 2.清华大学 |
| Recommended Citation GB/T 7714 | Cao Yang,Liang QiongLin,Zhang HongYang,et al. Screening and identification of multi-classified components in Liushenwan using multi-dimension high performance liquid chromatography tandem mass spectrometry system[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2008,36(1):39-46. |
| APA | Cao Yang,Liang QiongLin,Zhang HongYang,Wang YiMing,Bi KaiShun,&Luo GuoAn.(2008).Screening and identification of multi-classified components in Liushenwan using multi-dimension high performance liquid chromatography tandem mass spectrometry system.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,36(1),39-46. |
| MLA | Cao Yang,et al."Screening and identification of multi-classified components in Liushenwan using multi-dimension high performance liquid chromatography tandem mass spectrometry system".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 36.1(2008):39-46. |
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