Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae

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	Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae
其他题名	Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae
	Zhang Qi 1; Hua Gang 2; Adang Michael J 2
	2017
发表期刊	INSECT SCIENCE
ISSN	1672-9609
卷号	24 期号:5 页码:714-729
摘要	Bacillus thuringiensis is a Gram-positive aerobic bacterium that produces insecticidal crystalline inclusions during sporulation phases of the mother cell. The virulence factor, known as parasporal crystals, is composed of Cry and Cyt toxins. Most Cry toxins display a common 3-domain topology. Cry toxins exert intoxication through toxin activation, receptor binding and pore formation in a suitable larval gut environment. The mosquitocidal toxins of Bt subsp. israelensis (Bti) were found to be highly active against mosquito larvae and are widely used for vector control. Bt subsp. jegathesan is another strain which possesses high potency against broad range of mosquito larvae. The present review summarizes characterized receptors for Cry toxins in mosquito larvae, and will also discuss the diversity and effects of 3-D mosquitocidal Cry toxin and the ongoing research for Cry toxin mechanisms generated from investigations of lepidopteran and dipteran larvae.
其他摘要	Bacillus thuringiensis is a Gram-positive aerobic bacterium that produces insecticidal crystalline inclusions during sporulation phases of the mother cell. The virulence factor, known as parasporal crystals, is composed of Cry and Cyt toxins. Most Cry toxins display a common 3-domain topology. Cry toxins exert intoxication through toxin activation, receptor binding and pore formation in a suitable larval gut environment. The mosquitocidal toxins of Bt subsp. israelensis (Bti) were found to be highly active against mosquito larvae and are widely used for vector control. Bt subsp. jegathesan is another strain which possesses high potency against broad range of mosquito larvae. The present review summarizes characterized receptors for Cry toxins in mosquito larvae, and will also discuss the diversity and effects of 3-D mosquitocidal Cry toxin and the ongoing research for Cry toxin mechanisms generated from investigations of lepidopteran and dipteran larvae.
关键词	BRUSH-BORDER MEMBRANE SPHAERICUS BINARY TOXIN MALARIA VECTOR MOSQUITO AEDES-AEGYPTI LARVAE ALPHA-AMYLASE FAMILY ANCHORED ALKALINE-PHOSPHATASE MANDUCA-SEXTA AMINOPEPTIDASE ANOPHELES-GAMBIAE LARVAE DELTA-ENDOTOXIN BINDING CULEX-PIPIENS DIPTERA Bacillus thuringiensis Cry toxins mode of action mosquito receptors
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:6092281
引用统计	被引频次：2[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/150522
专题	中国科学院金属研究所
作者单位	1.中国科学院金属研究所 2.University Georgia, Dept Entomol, 427 Biol Sci, Athens, GA 30602 USA 3.中国科学院地质与地球物理研究所
推荐引用方式 GB/T 7714	Zhang Qi,Hua Gang,Adang Michael J. Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae[J]. INSECT SCIENCE,2017,24(5):714-729.
APA	Zhang Qi,Hua Gang,&Adang Michael J.(2017).Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae.INSECT SCIENCE,24(5),714-729.
MLA	Zhang Qi,et al."Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae".INSECT SCIENCE 24.5(2017):714-729.