| Hierarchical charge distribution controls self-assembly process of silk in vitro | |
| Alternative Title | Hierarchical charge distribution controls self-assembly process of silk in vitro |
| Zhang Yi1; Zhang Cencen1; Liu Lijie1; Kaplan David L1; Zhu Hesun4; Lu Qiang1 | |
| 2015 | |
| Source Publication | FRONTIERS OF MATERIALS SCIENCE
 |
| ISSN | 2095-025X |
| Volume | 9Issue:4Pages:382-391 |
| Abstract | Silk materials with different nanostructures have been developed without the understanding of the inherent transformation mechanism. Here we attempt to reveal the conversion road of the various nanostructures and determine the critical regulating factors. The regulating conversion processes influenced by a hierarchical charge distribution were investigated, showing different transformations between molecules, nanoparticles and nanofibers. Various repulsion and compressive forces existed among silk fibroin molecules and aggregates due to the exterior and interior distribution of charge, which further controlled their aggregating and deaggregating behaviors and finally formed nanofibers with different sizes. Synergistic action derived from molecular mobility and concentrations could also tune the assembly process and final nanostructures. It is suggested that the complicated silk fibroin assembly processes comply a same rule based on charge distribution, offering a promising way to develop silk-based materials with designed nanostructures. |
| Other Abstract | Silk materials with different nanostructures have been developed without the understanding of the inherent transformation mechanism. Here we attempt to reveal the conversion road of the various nanostructures and determine the critical regulating factors. The regulating conversion processes influenced by a hierarchical charqe distribution were investigated, showing different transformations between molecules, nanoparticles and nanofibers. Various repulsion and compressive forces existed among silk fibroin molecules and aggregates due to the exterior and interior distribution of charge,which further controlled their aggregating and deaggregating behaviors and finally formed nanofibers with different sizes. Synergistic action derived from molecular mobility and concentrations could also tune the assembly process and final nanostructures. It is suggested that the complicated silk fibroin assembly processes comply a same rule based on charge distribution, offering a promising way to develop silk-based materials with designed nanostructures. |
| Keyword | ATOMIC-FORCE MICROSCOPY SPIDER DRAGLINE SILK FIBROIN NANOFIBERS PROTEIN PH NANOSTRUCTURE MECHANISMS TOUGHNESS STRENGTH SCAFFOLDS silk self-assembly charge nanostructure nanofiber |
| Indexed By | CSCD |
| Language | 英语 |
| Funding Project | [National Basic Research Program of China (973 Program)] ; [National Natural Science Foundation of China] ; [Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)] ; [Excellent Youth Foundation of Jiangsu Province] ; [International S&T Cooperation Project of the Ministry of ST of China] ; [Key Natural Science Foundation of the Jiangsu Higher Education Institutions of China] ; [Jiangsu Provincial Special Program of Medical Science] |
| CSCD ID | CSCD:5594201 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/152316 |
| Collection | 中国科学院金属研究所 |
| Affiliation | 1.苏州大学 2.Henan Institute Engn, Coll Text, Zhengzhou 450007, Peoples R China 3.塔夫茨大学 4.中国科学院金属研究所 |
| Recommended Citation GB/T 7714 | Zhang Yi,Zhang Cencen,Liu Lijie,et al. Hierarchical charge distribution controls self-assembly process of silk in vitro[J]. FRONTIERS OF MATERIALS SCIENCE,2015,9(4):382-391. |
| APA | Zhang Yi,Zhang Cencen,Liu Lijie,Kaplan David L,Zhu Hesun,&Lu Qiang.(2015).Hierarchical charge distribution controls self-assembly process of silk in vitro.FRONTIERS OF MATERIALS SCIENCE,9(4),382-391. |
| MLA | Zhang Yi,et al."Hierarchical charge distribution controls self-assembly process of silk in vitro".FRONTIERS OF MATERIALS SCIENCE 9.4(2015):382-391. |
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