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A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel
Alternative TitleA new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel
Lu Jin Cai1; Xu Bei Bei1; Gao Song2; Kodama Hiroyuki3
2009
Source PublicationCHINESE CHEMICAL LETTERS
ISSN1001-8417
Volume20Issue:6Pages:694-697
AbstractA new triterpenoid saponins, raddeanoside R(19) (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R(19) on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA) in a different concentration-dependent manner. (C) 2008 Jin Cai Lu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
Other AbstractA new triterpenoid saponins, raddeanoside R_(19) (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R_(19) on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and araehidonic acid (AA) in a different concentration-dependent manner.
KeywordCHEMICAL-CONSTITUENTS SAPONINS Anemone raddeana Regel Raddeanoside R(19) Superoxide generation-inhibitor
Indexed ByCSCD
Language英语
Funding Project[National Natural Science Foundation of China] ; [Natural Science Foundation of Liaoning province of China]
CSCD IDCSCD:3757058
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/152552
Collection中国科学院金属研究所
Affiliation1.中国科学院金属研究所
2.中国科学院成都生物研究所
3.Kochi University, Dept Anesthesiol & Crit Care Med, Kochi 7838505, Japan
Recommended Citation
GB/T 7714
Lu Jin Cai,Xu Bei Bei,Gao Song,et al. A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel[J]. CHINESE CHEMICAL LETTERS,2009,20(6):694-697.
APA Lu Jin Cai,Xu Bei Bei,Gao Song,&Kodama Hiroyuki.(2009).A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel.CHINESE CHEMICAL LETTERS,20(6),694-697.
MLA Lu Jin Cai,et al."A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel".CHINESE CHEMICAL LETTERS 20.6(2009):694-697.
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