A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel | |
Alternative Title | A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel |
Lu Jin Cai1; Xu Bei Bei1; Gao Song2; Kodama Hiroyuki3 | |
2009 | |
Source Publication | CHINESE CHEMICAL LETTERS
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ISSN | 1001-8417 |
Volume | 20Issue:6Pages:694-697 |
Abstract | A new triterpenoid saponins, raddeanoside R(19) (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R(19) on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA) in a different concentration-dependent manner. (C) 2008 Jin Cai Lu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
Other Abstract | A new triterpenoid saponins, raddeanoside R_(19) (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R_(19) on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and araehidonic acid (AA) in a different concentration-dependent manner. |
Keyword | CHEMICAL-CONSTITUENTS SAPONINS Anemone raddeana Regel Raddeanoside R(19) Superoxide generation-inhibitor |
Indexed By | CSCD |
Language | 英语 |
Funding Project | [National Natural Science Foundation of China] ; [Natural Science Foundation of Liaoning province of China] |
CSCD ID | CSCD:3757058 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.imr.ac.cn/handle/321006/152552 |
Collection | 中国科学院金属研究所 |
Affiliation | 1.中国科学院金属研究所 2.中国科学院成都生物研究所 3.Kochi University, Dept Anesthesiol & Crit Care Med, Kochi 7838505, Japan |
Recommended Citation GB/T 7714 | Lu Jin Cai,Xu Bei Bei,Gao Song,et al. A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel[J]. CHINESE CHEMICAL LETTERS,2009,20(6):694-697. |
APA | Lu Jin Cai,Xu Bei Bei,Gao Song,&Kodama Hiroyuki.(2009).A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel.CHINESE CHEMICAL LETTERS,20(6),694-697. |
MLA | Lu Jin Cai,et al."A new superoxide-generation inhibitor from rhizome of Anemone raddeana Regel".CHINESE CHEMICAL LETTERS 20.6(2009):694-697. |
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