Alternative TitleScanning electron microscopy observation of the growth of osteoblasts on Ti-24Nb-4Zr-8Sn modified by micro-arc oxidation and alkali-heat treatment and implant-bone interface
韩雪1; 刘洪臣1; 王东胜1; 李述军2; 杨锐2
Source Publication中华口腔医学杂志
Abstract目的 通过观察微弧氧化-碱热处理后钛铌锆锡合金(Ti-24Nb-4Zr-8Sn)表面成骨细胞的生长情况和种植体-骨界面的结合情况,探讨对钛铌锆锡合金表面应用微弧氧化-碱热处理进行改性的效果.方法 用钛铌锆锡合金制备圆片形试件和圆柱形种植体各12个,均分为3个组(空白对照组、微弧氧化组和微弧氧化-碱热处理组)进行相应表面处理.将MC3T3-E1成骨样细胞接种于圆片形试件表面,培养3 d后扫描电镜(SEM)比较各组试件表面的细胞形态.将圆柱形种植体植入犬胫骨内,3个月后SEM观察种植体-骨界面的微观形貌.结果 微弧氧化和微弧氧化-碱热处理均可使钛铌锆锡合金表面生成具有生成微孔结构的氧化膜,后者试件表面的细胞与微孔嵌合更紧密,种植体与骨组织形成良好的骨结合.结论 碱热处理可进一步完善微弧氧化方法,提高种植体与骨界面的结合.
Other AbstractObjective To observe the efficacy of micro-arc oxidation and alkali-heat treatment (MAH) on Ti-24Nb-4Zr-8Sn(Ti2448). Methods Disks( diameter of 14. 5 mm, thickness of 1 mm) and cylinders (diameter of 3 mm, height of 10 mm) were fabricated from Ti2448 alloy. Samples were divided into three groups: polished( Ti2448 ), micro-arc oxidation( MAO-Ti2448 ), micro-arc oxidation and alkali-heat treatment(MAH-Ti2448). MC3T3-E1 osteoblastic cells were cultured on the disks and cell morphology was observed with scanning electron microscopy(SEM) aftre 3 days. The cylinder samples were implanted in the tibia of dogs and implant-bone interface was observed with SEM after 3 months. Results A rough and porous structure was shown in both MAO and MAH group. The MC3T3-E1 cells on the MAH-Ti2448 discs spread fully in intimate contact with the underlying coarse surface through active cytoskeletal extentions.Osseointegration was formed in the implant-bone interface in MAH samples. Conclusions MAH treatment can provide a more advantageous Ti2448 surface to osteoblastic cells than MAO treatment does, and the former can improve the implant-bone integration.
Keyword 显微镜检查,电子,扫描 微弧氧化 碱热处理
Indexed ByCSCD
Citation statistics
Cited Times:2[CSCD]   [CSCD Record]
Document Type期刊论文
Recommended Citation
GB/T 7714
韩雪,刘洪臣,王东胜,等. 微弧氧化-碱热处理后钛铌锆锡合金种植体-骨界面的扫描电镜观察[J]. 中华口腔医学杂志,2011,46.0(1.0):50-53.
APA 韩雪,刘洪臣,王东胜,李述军,&杨锐.(2011).微弧氧化-碱热处理后钛铌锆锡合金种植体-骨界面的扫描电镜观察.中华口腔医学杂志,46.0(1.0),50-53.
MLA 韩雪,et al."微弧氧化-碱热处理后钛铌锆锡合金种植体-骨界面的扫描电镜观察".中华口腔医学杂志
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[韩雪]'s Articles
[刘洪臣]'s Articles
[王东胜]'s Articles
Baidu academic
Similar articles in Baidu academic
[韩雪]'s Articles
[刘洪臣]'s Articles
[王东胜]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[韩雪]'s Articles
[刘洪臣]'s Articles
[王东胜]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.