IMR OpenIR
Catalytic synthesis methods for triazolopyrimidine derivatives
Alternative TitleCatalytic Synthesis Methods for Triazolopyrimidine Derivatives
Cheng ChunSheng; Gai YongMing; Wang XinLei; Peng Jun
2008
Source PublicationCHINESE JOURNAL OF CHEMISTRY
ISSN1001-604X
Volume26Issue:7Pages:1291-1294
AbstractA new method for catalyzed synthesis of triazolopyrimidine derivatives is reported. Alkylamine reaction with dialkyl cyanodithioiminocarbonate was catalyzed by quaternary ammonium salts at room temperature to yield 3-alkylamine-5-amino-1,2,4-triazole in good quality and high yields. After imidization and reaction with an alpha,beta-unsaturated acid derivative, the reaction intermediate was hydrolyzed in the presence of a Lewis acid to obtain the target product. This novel catalytic method for triazolopyrimidine derivatives can be carried out under inexpensive and mild conditions, and is safe and environmentally friendly. (1)H NMR results for all intermediates are reported.
Other AbstractA new method for catalyzed synthesis of triazolopyrimidine derivatives is reported. Alkylamine reaction with dialkyl cyanodithioiminocarbonate was catalyzed by quaternary ammonium salts at room temperature to yield 3-alkylamine-5-amino-1,2,4-triazole in good quality and high yields. After imidization and reaction with an ,-unsaturated acid derivative, the reaction intermediate was hydrolyzed in the presence of a Lewis acid to obtain the target product. This novel catalytic method for triazolopyrimidine derivatives can be carried out under inexpensive and mild conditions, and is safe and environmentally friendly. 1H NMR results for all intermediates are reported.
KeywordPARAQUAT triazolopyrimidine derivative catalyst Lewis acid green chemistry
Indexed ByCSCD
Language英语
CSCD IDCSCD:3434908
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/153776
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Cheng ChunSheng,Gai YongMing,Wang XinLei,et al. Catalytic synthesis methods for triazolopyrimidine derivatives[J]. CHINESE JOURNAL OF CHEMISTRY,2008,26(7):1291-1294.
APA Cheng ChunSheng,Gai YongMing,Wang XinLei,&Peng Jun.(2008).Catalytic synthesis methods for triazolopyrimidine derivatives.CHINESE JOURNAL OF CHEMISTRY,26(7),1291-1294.
MLA Cheng ChunSheng,et al."Catalytic synthesis methods for triazolopyrimidine derivatives".CHINESE JOURNAL OF CHEMISTRY 26.7(2008):1291-1294.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Cheng ChunSheng]'s Articles
[Gai YongMing]'s Articles
[Wang XinLei]'s Articles
Baidu academic
Similar articles in Baidu academic
[Cheng ChunSheng]'s Articles
[Gai YongMing]'s Articles
[Wang XinLei]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Cheng ChunSheng]'s Articles
[Gai YongMing]'s Articles
[Wang XinLei]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.