Synthesis of 3-aminomethyl-4-trifluoromethylpyridine

IMR OpenIR

	Synthesis of 3-aminomethyl-4-trifluoromethylpyridine
其他题名	Synthesis of 3-Aminomethyl-4-trifluoromethylpyridine
	Li Jie; Chen Hao; Zhou Xun; Lu XiuHong; Chen GuoLiang
	2008
发表期刊	CHINESE JOURNAL OF ORGANIC CHEMISTRY
ISSN	0253-2786
卷号	28 期号:9 页码:1637-1640
摘要	A new convenient synthesis of 3-aminomethyl-4-trifluoromethylpyridine using 4,4,4-trifluoroacetoacetate and cyanoacetamide as precursors, via cyclization, chlorination, hydrogenolysis and hydrogenation under mild conditions, was achieved. In comparison with other methods, there are some advantages in this method: low-cost, easy purification, low equipment requirements and suitability for industrial scale-up.
关键词	4,4,4-trifluoroacetoacetate 3-aminomethyl-4-trifluoromethylpyridine synthesis
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:3395375
引用统计	被引频次：3[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/153956
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Li Jie,Chen Hao,Zhou Xun,et al. Synthesis of 3-aminomethyl-4-trifluoromethylpyridine[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2008,28(9):1637-1640.
APA	Li Jie,Chen Hao,Zhou Xun,Lu XiuHong,&Chen GuoLiang.(2008).Synthesis of 3-aminomethyl-4-trifluoromethylpyridine.CHINESE JOURNAL OF ORGANIC CHEMISTRY,28(9),1637-1640.
MLA	Li Jie,et al."Synthesis of 3-aminomethyl-4-trifluoromethylpyridine".CHINESE JOURNAL OF ORGANIC CHEMISTRY 28.9(2008):1637-1640.