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One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans
Alternative TitleOne new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans
Li Qiao; Yu Zhi Zhou; Huan Chen; Jia Qing Cao; Yue Hu Pei
2008
Source PublicationCHINESE CHEMICAL LETTERS
ISSN1001-8417
Volume19Issue:3Pages:299-301
AbstractCunninghamella elegans has been employed for the biotransformation of cinobufagin (1) to afford one metabolites. The structure of the transformation product has been characterized as 7 beta,12 beta-dihydroxylcinobufagin (2). Product 2 is a new compound. In vitro cytotoxic activities of the biotransformation product and the substrate-cinobufagin have been assayed against HeLa; they all showed cytotoxic activities. (c) 2007 Yue Hu Pei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
Other AbstractCunninghamella elegans has been employed for the biotransformation of cinobufagin (1) to afford one metabolites. The structure of the transformation product has been characterized as 7β,12β-dihydroxylcinobufagin (2). Product 2 is a new compound. In vitro cytotoxic activities of the biotransformation product and the substrate-cinobufagin have been assayed against HeLa; they all showed cytotoxic activities.
Keywordbiotransformation cinobufagin 7 beta,12 beta-dihydroxylcinobufagin Cunninghamella elegans
Indexed ByCSCD
Language英语
CSCD IDCSCD:3579501
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/154797
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Li Qiao,Yu Zhi Zhou,Huan Chen,et al. One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans[J]. CHINESE CHEMICAL LETTERS,2008,19(3):299-301.
APA Li Qiao,Yu Zhi Zhou,Huan Chen,Jia Qing Cao,&Yue Hu Pei.(2008).One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans.CHINESE CHEMICAL LETTERS,19(3),299-301.
MLA Li Qiao,et al."One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans".CHINESE CHEMICAL LETTERS 19.3(2008):299-301.
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