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One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans
其他题名One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans
Li Qiao; Yu Zhi Zhou; Huan Chen; Jia Qing Cao; Yue Hu Pei
2008
发表期刊CHINESE CHEMICAL LETTERS
ISSN1001-8417
卷号19期号:3页码:299-301
摘要Cunninghamella elegans has been employed for the biotransformation of cinobufagin (1) to afford one metabolites. The structure of the transformation product has been characterized as 7 beta,12 beta-dihydroxylcinobufagin (2). Product 2 is a new compound. In vitro cytotoxic activities of the biotransformation product and the substrate-cinobufagin have been assayed against HeLa; they all showed cytotoxic activities. (c) 2007 Yue Hu Pei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
其他摘要Cunninghamella elegans has been employed for the biotransformation of cinobufagin (1) to afford one metabolites. The structure of the transformation product has been characterized as 7β,12β-dihydroxylcinobufagin (2). Product 2 is a new compound. In vitro cytotoxic activities of the biotransformation product and the substrate-cinobufagin have been assayed against HeLa; they all showed cytotoxic activities.
关键词biotransformation cinobufagin 7 beta,12 beta-dihydroxylcinobufagin Cunninghamella elegans
收录类别CSCD
语种英语
CSCD记录号CSCD:3579501
引用统计
文献类型期刊论文
条目标识符http://ir.imr.ac.cn/handle/321006/154797
专题中国科学院金属研究所
作者单位中国科学院金属研究所
推荐引用方式
GB/T 7714
Li Qiao,Yu Zhi Zhou,Huan Chen,et al. One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans[J]. CHINESE CHEMICAL LETTERS,2008,19(3):299-301.
APA Li Qiao,Yu Zhi Zhou,Huan Chen,Jia Qing Cao,&Yue Hu Pei.(2008).One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans.CHINESE CHEMICAL LETTERS,19(3),299-301.
MLA Li Qiao,et al."One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans".CHINESE CHEMICAL LETTERS 19.3(2008):299-301.
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