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Computer aided modeling and pore distribution of bionic porous bone structure
Alternative TitleComputer aided modeling and pore distribution of bionic porous bone structure
Li Hu1; Yang Jianyu1; Su Pengcheng2; Wang Wanshan1
2012
Source PublicationJOURNAL OF CENTRAL SOUTH UNIVERSITY
ISSN2095-2899
Volume19Issue:12Pages:3492-3499
AbstractArtificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way.
Other AbstractArtificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way.
KeywordFINITE-ELEMENT TISSUE SCAFFOLD DESIGN CELLS tissue scaffold geometry modeling porous structure compute aided design optimal design clinic implants
Indexed ByCSCD
Language英语
Funding Project[State International Cooperation Program of China] ; [Basic Research Foundation of Education Ministry of China]
CSCD IDCSCD:4705812
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/154918
Collection中国科学院金属研究所
Affiliation1.东北大学
2.中国科学院金属研究所
Recommended Citation
GB/T 7714
Li Hu,Yang Jianyu,Su Pengcheng,et al. Computer aided modeling and pore distribution of bionic porous bone structure[J]. JOURNAL OF CENTRAL SOUTH UNIVERSITY,2012,19(12):3492-3499.
APA Li Hu,Yang Jianyu,Su Pengcheng,&Wang Wanshan.(2012).Computer aided modeling and pore distribution of bionic porous bone structure.JOURNAL OF CENTRAL SOUTH UNIVERSITY,19(12),3492-3499.
MLA Li Hu,et al."Computer aided modeling and pore distribution of bionic porous bone structure".JOURNAL OF CENTRAL SOUTH UNIVERSITY 19.12(2012):3492-3499.
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