Computer aided modeling and pore distribution of bionic porous bone structure

IMR OpenIR

	Computer aided modeling and pore distribution of bionic porous bone structure
其他题名	Computer aided modeling and pore distribution of bionic porous bone structure
	Li Hu 1; Yang Jianyu 1; Su Pengcheng 2; Wang Wanshan 1
	2012
发表期刊	JOURNAL OF CENTRAL SOUTH UNIVERSITY
ISSN	2095-2899
卷号	19 期号:12 页码:3492-3499
摘要	Artificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way.
其他摘要	Artificial bone with porous structure is crucial for tissue scaffold and clinic implants. Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure. A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture, porosity and pore size. To simulate intricate bone structure, different constructive units were presented. In modeling process, bone contour was gotten from computed tomography (CT) images and was divided into two levels. Each level was represented by relatively reconstructive process. Pore size distribution was controlled by using mesh generation. The whole hexahedral mesh was reduced by unit structure, when a 3D mesh with various hexahedral elements was provided. The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way.
关键词	FINITE-ELEMENT TISSUE SCAFFOLD DESIGN CELLS tissue scaffold geometry modeling porous structure compute aided design optimal design clinic implants
收录类别	CSCD
语种	英语
资助项目	[State International Cooperation Program of China] ; [Basic Research Foundation of Education Ministry of China]
CSCD记录号	CSCD:4705812
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/154920
专题	中国科学院金属研究所
作者单位	1.东北大学 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Li Hu,Yang Jianyu,Su Pengcheng,et al. Computer aided modeling and pore distribution of bionic porous bone structure[J]. JOURNAL OF CENTRAL SOUTH UNIVERSITY,2012,19(12):3492-3499.
APA	Li Hu,Yang Jianyu,Su Pengcheng,&Wang Wanshan.(2012).Computer aided modeling and pore distribution of bionic porous bone structure.JOURNAL OF CENTRAL SOUTH UNIVERSITY,19(12),3492-3499.
MLA	Li Hu,et al."Computer aided modeling and pore distribution of bionic porous bone structure".JOURNAL OF CENTRAL SOUTH UNIVERSITY 19.12(2012):3492-3499.