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Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?
Alternative TitleEarly PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful
Liu Zhaoyu; Chang Zhihui; Lu Zaiming; Guo Qiyong
2010
Source PublicationCHINESE MEDICAL JOURNAL
ISSN0366-6999
Volume123Issue:13Pages:1690-1694
AbstractBackground Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early (18)F-FDG PET/CT scanning to monitor the effectiveness of RFA in colorectal liver metastases.
Other AbstractBackground Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early 18F-FDG PET/CT scanning to monitor the effectiveness of RFA in colorectal liver metastases. Methods Twelve patients with 20 metastases were treated with RFA for colorectal liver metastases. They underwent PET/CT within 2 weeks before RFA and within 24 hours after RFA (so termed "early PET/CT'). PET/CT was repeated at 1, 3, and 6 months, and then every 6 months after ablation. The standard of reference was based on available clinical and radiological follow-up data. Results Early PET/CT revealed total photopenia in 16 RFA-treated metastases, which were found to be without residual tumor on the final PET/CT scan. Three RFA-treated metastases with focal uptake were identified as local tumor progression, which necessitated further treatment. One RFA-treated metastasis with rim-shaped uptake was regarded as inflammation. The results of the early PET/CT scanning were consistent with the findings of the final follow-up. Conclusions PET/CT performed within 24 hours after RFA can effectively detect whether residual tumor exists for colorectal cancer liver metastases. The results can guide further treatment, and may improve the efficacy of RFA
KeywordPOSITRON-EMISSION-TOMOGRAPHY HEPATOCELLULAR-CARCINOMA HEPATIC METASTASES SURGICAL RESECTION THERMAL ABLATION TUMOR RECURRENCE SPECTRUM THERAPY TISSUE RISK Fluorodeoxyglucose (18)F-FDG PET/CT colorectal neoplasms liver metastasis radiofrequency ablation
Indexed ByCSCD
Language英语
CSCD IDCSCD:3965997
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/155754
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Liu Zhaoyu,Chang Zhihui,Lu Zaiming,et al. Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?[J]. CHINESE MEDICAL JOURNAL,2010,123(13):1690-1694.
APA Liu Zhaoyu,Chang Zhihui,Lu Zaiming,&Guo Qiyong.(2010).Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?.CHINESE MEDICAL JOURNAL,123(13),1690-1694.
MLA Liu Zhaoyu,et al."Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?".CHINESE MEDICAL JOURNAL 123.13(2010):1690-1694.
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