Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?

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	Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?
其他题名	Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful
	Liu Zhaoyu; Chang Zhihui; Lu Zaiming; Guo Qiyong
	2010
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
卷号	123 期号:13 页码:1690-1694
摘要	Background Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early (18)F-FDG PET/CT scanning to monitor the effectiveness of RFA in colorectal liver metastases.
其他摘要	Background Morphologic imaging after radiofrequency ablation (RFA) of liver metastases is hampered by an inflammatory response in the ablation margin, making the identification of local tumor progression (LTP) difficult. The aim of this study was to evaluate the efficacy of early 18F-FDG PET/CT scanning to monitor the effectiveness of RFA in colorectal liver metastases. Methods Twelve patients with 20 metastases were treated with RFA for colorectal liver metastases. They underwent PET/CT within 2 weeks before RFA and within 24 hours after RFA (so termed "early PET/CT'). PET/CT was repeated at 1, 3, and 6 months, and then every 6 months after ablation. The standard of reference was based on available clinical and radiological follow-up data. Results Early PET/CT revealed total photopenia in 16 RFA-treated metastases, which were found to be without residual tumor on the final PET/CT scan. Three RFA-treated metastases with focal uptake were identified as local tumor progression, which necessitated further treatment. One RFA-treated metastasis with rim-shaped uptake was regarded as inflammation. The results of the early PET/CT scanning were consistent with the findings of the final follow-up. Conclusions PET/CT performed within 24 hours after RFA can effectively detect whether residual tumor exists for colorectal cancer liver metastases. The results can guide further treatment, and may improve the efficacy of RFA
关键词	POSITRON-EMISSION-TOMOGRAPHY HEPATOCELLULAR-CARCINOMA HEPATIC METASTASES SURGICAL RESECTION THERMAL ABLATION TUMOR RECURRENCE SPECTRUM THERAPY TISSUE RISK Fluorodeoxyglucose (18)F-FDG PET/CT colorectal neoplasms liver metastasis radiofrequency ablation
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:3965997
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/155754
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Liu Zhaoyu,Chang Zhihui,Lu Zaiming,et al. Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?[J]. CHINESE MEDICAL JOURNAL,2010,123(13):1690-1694.
APA	Liu Zhaoyu,Chang Zhihui,Lu Zaiming,&Guo Qiyong.(2010).Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?.CHINESE MEDICAL JOURNAL,123(13),1690-1694.
MLA	Liu Zhaoyu,et al."Early PET/CT after radiofrequency ablation in colorectal cancer liver metastases: is it useful?".CHINESE MEDICAL JOURNAL 123.13(2010):1690-1694.