Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer | |
Alternative Title | Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer |
Bu Xianmin; Zhao Chenghai; Dai Xianwei | |
2008 | |
Source Publication | CHINESE MEDICAL JOURNAL
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ISSN | 0366-6999 |
Volume | 121Issue:10Pages:952-955 |
Abstract | Pancreatic cancer is one of the malignant tumor with a very poor prognosis. Both genetic and epigenetic alterations are involved in the pathogenetic mechanisms of pancreatic cancer. Hypermethylation and subsequent loss of expression of some tumor suppressor genes and tumor-related genes occur frequently in pancreatic cancer, such as loss of expression of pl6,1 RASSF1A,2 SOCS-1,3 and hMLH14 genes were repoted. |
Other Abstract | Pancreatic cancer is one of the malignant tumor with a very poor prognosis. Both genetic and epigenetic alterations are involved in the pathogenetic mechanisms of pancreatic cancer. Hypermethylation and subsequent loss of expression of some tumor suppressor genes and tumor-related genes occur frequently in pancreatic cancer, such as loss of expression of pl6,1 RASSF1A,2 SOCS-1,3 and hMLH14 genes were repoted. |
Keyword | PROSTATE-CANCER GENE METHYLATION HYPERMETHYLATION TUMORIGENESIS CARCINOMA SFRP1 Wnt hypermethylation pancreatic cancer |
Indexed By | CSCD |
Language | 英语 |
CSCD ID | CSCD:3383548 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.imr.ac.cn/handle/321006/157559 |
Collection | 中国科学院金属研究所 |
Affiliation | 中国科学院金属研究所 |
Recommended Citation GB/T 7714 | Bu Xianmin,Zhao Chenghai,Dai Xianwei. Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer[J]. CHINESE MEDICAL JOURNAL,2008,121(10):952-955. |
APA | Bu Xianmin,Zhao Chenghai,&Dai Xianwei.(2008).Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer.CHINESE MEDICAL JOURNAL,121(10),952-955. |
MLA | Bu Xianmin,et al."Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer".CHINESE MEDICAL JOURNAL 121.10(2008):952-955. |
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