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Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer
Alternative TitleAberrant expression of Wnt antagonist SFRP1 in pancreatic cancer
Bu Xianmin; Zhao Chenghai; Dai Xianwei
2008
Source PublicationCHINESE MEDICAL JOURNAL
ISSN0366-6999
Volume121Issue:10Pages:952-955
AbstractPancreatic cancer is one of the malignant tumor with a very poor prognosis. Both genetic and epigenetic alterations are involved in the pathogenetic mechanisms of pancreatic cancer. Hypermethylation and subsequent loss of expression of some tumor suppressor genes and tumor-related genes occur frequently in pancreatic cancer, such as loss of expression of pl6,1 RASSF1A,2 SOCS-1,3 and hMLH14 genes were repoted.
Other AbstractPancreatic cancer is one of the malignant tumor with a very poor prognosis. Both genetic and epigenetic alterations are involved in the pathogenetic mechanisms of pancreatic cancer. Hypermethylation and subsequent loss of expression of some tumor suppressor genes and tumor-related genes occur frequently in pancreatic cancer, such as loss of expression of pl6,1 RASSF1A,2 SOCS-1,3 and hMLH14 genes were repoted.
KeywordPROSTATE-CANCER GENE METHYLATION HYPERMETHYLATION TUMORIGENESIS CARCINOMA SFRP1 Wnt hypermethylation pancreatic cancer
Indexed ByCSCD
Language英语
CSCD IDCSCD:3383548
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/157559
Collection中国科学院金属研究所
Affiliation中国科学院金属研究所
Recommended Citation
GB/T 7714
Bu Xianmin,Zhao Chenghai,Dai Xianwei. Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer[J]. CHINESE MEDICAL JOURNAL,2008,121(10):952-955.
APA Bu Xianmin,Zhao Chenghai,&Dai Xianwei.(2008).Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer.CHINESE MEDICAL JOURNAL,121(10),952-955.
MLA Bu Xianmin,et al."Aberrant expression of Wnt antagonist SFRP1 in pancreatic cancer".CHINESE MEDICAL JOURNAL 121.10(2008):952-955.
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