| Antibacterial behavior and related mechanisms of martensitic Cu-bearing stainless steel evaluated by a mixed infection model of C Escherichia coli and Staphylococcus aureus in vitro | |
| Li, Mingjun1,2; Nan, Li2; Liang, Chunyong1; Sun, Ziqing2; Yang, Lei1,3; Yang, Ke2 | |
| Corresponding Author | Yang, Lei(ylei@hebut.edu.cn) ; Yang, Ke(kyang@imr.ac.cn) |
| 2021-01-30 | |
| Source Publication | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
 |
| ISSN | 1005-0302 |
| Volume | 62Pages:139-147 |
| Abstract | Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) are the most typical pathogenic bacteria with a significantly high risk of bio-contamination, widely existing in hospital and public places. Recent studies on antibacterial materials and the related mechanisms have attracted more interests of researchers. However, the antibacterial behavior of materials is usually evaluated separately on the single bacterial strain, which is far from the practical condition. Actually, the interaction between the polymicrobial communities can promote the growing profile of bacteria, which may weaken the antibacterial effect of materials. In this work, a 420 copper-bearing martensitic stainless steel (420CuSS) was studied with respect to its antibacterial activity and the underlying mechanism in a co-culturing infection model using both E. coli and S. aureus. Observed via plating and counting colony forming units (CFU), Cu releasing, and material characterization, 420CuSS was proved to present excellent antibacterial performance against the mixed bacteria with an approximately 99.4 % of antibacterial rate. In addition, 420CuSS could effectively inhibit the biofilm formation on its surfaces, resulting from a synergistic antibacterial effect of Cu ions, Fe ions, reactive oxygen species (ROS), and proton consumption of bacteria. (C) 2020 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology. |
| Keyword | Mixed bacterial strains E. coli S. aureus 420 Cu-bearing stainless steel Antibacterial mechanism |
| Funding Organization | National Natural Science Foundation of China ; National Basic Research Program of China ; National Key R&D Program of China |
| DOI | 10.1016/j.jmst.2020.05.030 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[51101154] ; National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[51672184] ; National Natural Science Foundation of China[51371168] ; National Basic Research Program of China[2012CB619101] ; National Key R&D Program of China[2020YFC1107400] |
| WOS Research Area | Materials Science ; Metallurgy & Metallurgical Engineering |
| WOS Subject | Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering |
| WOS ID | WOS:000601221700014 |
| Publisher | JOURNAL MATER SCI TECHNOL |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/158830 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Yang, Lei; Yang, Ke |
| Affiliation | 1.Hebei Univ Technol, Ctr Hlth Sci & Engn, Sch Mat Sci & Engn, Tianjin 300130, Peoples R China 2.Univ Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 3.Int Res Ctr Translat Orthopaed IRCTO, Suzhou, Peoples R China |
| Recommended Citation GB/T 7714 | Li, Mingjun,Nan, Li,Liang, Chunyong,et al. Antibacterial behavior and related mechanisms of martensitic Cu-bearing stainless steel evaluated by a mixed infection model of C Escherichia coli and Staphylococcus aureus in vitro[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2021,62:139-147. |
| APA | Li, Mingjun,Nan, Li,Liang, Chunyong,Sun, Ziqing,Yang, Lei,&Yang, Ke.(2021).Antibacterial behavior and related mechanisms of martensitic Cu-bearing stainless steel evaluated by a mixed infection model of C Escherichia coli and Staphylococcus aureus in vitro.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,62,139-147. |
| MLA | Li, Mingjun,et al."Antibacterial behavior and related mechanisms of martensitic Cu-bearing stainless steel evaluated by a mixed infection model of C Escherichia coli and Staphylococcus aureus in vitro".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 62(2021):139-147. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment