| A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection | |
| Hao, Yabin1,2; Fang, Minghe1,2; Xu, Chuan1; Ying, Zhe1; Wang, Han1,2; Zhang, Rui3; Cheng, Hui-Ming1,2,4; Zeng, You1,2 | |
| Corresponding Author | Zhang, Rui(zzzrrr1234@sina.com) ; Cheng, Hui-Ming(cheng@imr.ac.cn) ; Zeng, You(yzeng@imr.ac.cn) |
| 2021-03-10 | |
| Source Publication | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
 |
| ISSN | 1005-0302 |
| Volume | 66Pages:57-63 |
| Abstract | Graphene oxide (GO) has received considerable attention for glucose detection because of high surface area, abundant functional groups, and good biocompatibility. Defects and functional groups of the GO are beneficial to immobilization of glucose oxidase (GOD), but sacrificing electron-transfer capability for highly-sensitive detection. In order to obtain high GOD loading and highly-sensitive detection of biosensors, we first designed and fabricated a graphene-laminated electrode by combining GO and edge-functionalized graphene (FG) layers together onto glassy-carbon electrode. The graphene-laminated electrodes exhibited faster electron transfer rate, higher GOD loading of 3.80 x 10(-)(9) mol.cm(-2), and higher detection sensitivity of 46.71 mu A.mM(-1).cm(-2) than other graphene-based biosensors reported in literature. Such high performance is mainly attributed to the abundant functional groups of GO, high electrical conductivity of FG, and strong interactions between components in the graphene-laminated electrodes. By virtue of their high enzyme loading and highly-sensitive detection, the graphene-laminated electrodes show great potential to be widely used as high-performance biosensors in the field of medical diagnosis. (C) 2021 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology. |
| Keyword | Graphene Laminated structure Electrode Glucose detection Biosensor |
| Funding Organization | National Natural Science Foundation of China ; Liaoning Natural Science Foundation ; Liaoning Key Research & Development Project ; Joint Fund for Advanced Equipment and Aerospace Science and Technology of China |
| DOI | 10.1016/j.jmst.2020.04.070 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[51802317] ; Liaoning Natural Science Foundation[2019JH3/30100008] ; Liaoning Key Research & Development Project[2019JH2/10300045] ; Joint Fund for Advanced Equipment and Aerospace Science and Technology of China[6141B061306] |
| WOS Research Area | Materials Science ; Metallurgy & Metallurgical Engineering |
| WOS Subject | Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering |
| WOS ID | WOS:000610200200007 |
| Publisher | JOURNAL MATER SCI TECHNOL |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/159109 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Zhang, Rui; Cheng, Hui-Ming; Zeng, You |
| Affiliation | 1.Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Peoples R China 3.Liaoning Canc Hosp & Inst, Shenyang 110042, Peoples R China 4.Tsinghua Berkeley Shenzhen Inst, Shenzhen Geim Graphene Ctr, Shenzhen 518055, Peoples R China |
| Recommended Citation GB/T 7714 | Hao, Yabin,Fang, Minghe,Xu, Chuan,et al. A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2021,66:57-63. |
| APA | Hao, Yabin.,Fang, Minghe.,Xu, Chuan.,Ying, Zhe.,Wang, Han.,...&Zeng, You.(2021).A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,66,57-63. |
| MLA | Hao, Yabin,et al."A graphene-laminated electrode with high glucose oxidase loading for highly-sensitive glucose detection".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 66(2021):57-63. |
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