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Adipose-derived stem cells cooperate with fractional carbon dioxide laser in antagonizing photoaging: a potential role of Wnt and β-catenin signaling
Alternative TitleAdipose-derived stem cells cooperate with fractional carbon dioxide laser in antagonizing photoaging: a potential role of Wnt and β-catenin signaling
Xiao Xu1; Hong-yi Wang1; Yu Zhang1; Yang Liu2; Yan-qi Li2; Kai Tao1; Chu-Tse Wu2; Ji-de Jin2; Xiao-yan Liu1
2014-01-01
Source PublicationCell & Bioscience
ISSN2045-3701
Volume4Issue:1Pages:24-24
AbstractIt is well established that adipose-derived stem cells (ADSCs) produce and secrete cytokines 2 ) laser to facilitate photoaging skin healing process has not been explored. Here, we investigated the impacts of ADSCs on photoaging in a photoaging animal model, its associated mechanisms, and its functional cooperation with fractional CO 2 laser in treatment of photoaging skin.
Other AbstractBackground It is well established that adipose-derived stem cells (ADSCs) produce and secrete cytokines 2 ) laser to facilitate photoaging skin healing process has not been explored. Here, we investigated the impacts of ADSCs on photoaging in a photoaging animal model, its associated mechanisms, and its functional cooperation with fractional CO 2 laser in treatment of photoaging skin. Results We showed that ADSCs improved dermal thickness and activated the proliferation of dermal fibroblast. We further demonstrated that the combined treatment of ADSCs and fractional CO 2 laser, the latter which is often used to resurface skin and treat wrinkles, had more beneficial effects on the photoaging skin compared with each individual treatment. In our prepared HDF photoaging model, flow cytometry showed that, after adipose derived stem cells conditioned medium (ADSC-CM) co-cultured HDF photoaging model, the cell proliferation rate is higher than UVB irradiation induced HDF modeling (p?
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/159361
Collection中国科学院金属研究所
Affiliation1.中国科学院金属研究所
2.Institute of Radiation Medicine
Recommended Citation
GB/T 7714
Xiao Xu,Hong-yi Wang,Yu Zhang,et al. Adipose-derived stem cells cooperate with fractional carbon dioxide laser in antagonizing photoaging: a potential role of Wnt and β-catenin signaling[J]. Cell & Bioscience,2014,4(1):24-24.
APA Xiao Xu.,Hong-yi Wang.,Yu Zhang.,Yang Liu.,Yan-qi Li.,...&Xiao-yan Liu.(2014).Adipose-derived stem cells cooperate with fractional carbon dioxide laser in antagonizing photoaging: a potential role of Wnt and β-catenin signaling.Cell & Bioscience,4(1),24-24.
MLA Xiao Xu,et al."Adipose-derived stem cells cooperate with fractional carbon dioxide laser in antagonizing photoaging: a potential role of Wnt and β-catenin signaling".Cell & Bioscience 4.1(2014):24-24.
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