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Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant
Zhang, Shuyuan1; Yu, Yachuan2; Wang, Hai1; Ren, Ling1; Yang, Ke1
Corresponding AuthorRen, Ling() ; Yang, Ke(kyang@imr.ac.cn)
2022
Source PublicationJOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
ISSN1751-6161
Volume125Pages:6
AbstractCu-bearing titanium alloy has been proved to have excellent antibacterial properties, which can effectively reduce the incidence of infection caused by implantation. On the other hand, the addition of Cu in the titanium alloy can also significantly improve the strength of the alloy due to the dispersed precipitation of Ti2Cu compounds in matrix, which will enhance the biomechanical safety of Cu-bearing antibacterial titanium alloys. In this study, a Ti6Al4V5Cu antibacterial titanium alloy and the ordinary Ti6Al4V titanium alloy were used to make a variety of orthopedic trauma repair implants, including bone pin, bone screw and bone plate. Through the internationally accepted test methods, the mechanical properties such as tension, torsion and bending of the implants were studied, and the difference between the implants made of two materials was analyzed. The results showed that the tensile strength of Ti6Al4V5Cu pin was 25% higher than that of Ti6Al4V pin, the torsion strength of the screw was increased up to 89%, the static bending load of the plate was increased by 67-89%, and the maximum loading force of the plate after 1 million cycles of four point dynamic bending was increased by 41-91%. The above improvements should be attributed to the strengthening effect of Cu in the antibacterial titanium alloy, indicating that the Cu-bearing antibacterial titanium alloy implant possesses both advantages of reducing the bacterial infection and improving the biomechanical safety, and a broad clinical application prospects.
KeywordCu-bearing antibacterial titanium alloy Orthopedic implant Mechanical properties
Funding OrganizationNatural Science Foundation of China ; National Key Research and Development Program of China
DOI10.1016/j.jmbbm.2021.104926
Indexed BySCI
Language英语
Funding ProjectNatural Science Foundation of China[51631009] ; Natural Science Foundation of China[31870954] ; National Key Research and Development Program of China[2018YFC1106600] ; National Key Research and Development Program of China[2016YFC1100600]
WOS Research AreaEngineering ; Materials Science
WOS SubjectEngineering, Biomedical ; Materials Science, Biomaterials
WOS IDWOS:000717929700002
PublisherELSEVIER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/167436
Collection中国科学院金属研究所
Corresponding AuthorRen, Ling; Yang, Ke
Affiliation1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
2.Suzhou Silvan Med Co Ltd, Suzhou 215000, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Shuyuan,Yu, Yachuan,Wang, Hai,et al. Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant[J]. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS,2022,125:6.
APA Zhang, Shuyuan,Yu, Yachuan,Wang, Hai,Ren, Ling,&Yang, Ke.(2022).Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant.JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS,125,6.
MLA Zhang, Shuyuan,et al."Study on mechanical behavior of Cu-bearing antibacterial titanium alloy implant".JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS 125(2022):6.
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