Upconversion nanoparticles@single-walled carbon nanotubes composites as efficient self-monitored photo-thermal agents

doi:10.1016/j.saa.2023.123173

IMR OpenIR

	Upconversion nanoparticles@single-walled carbon nanotubes composites as efficient self-monitored photo-thermal agents
	Xu, Yang 1; Zou, Mengke 2,3; Wang, Hong 1; Zhang, Lili 2; Xing, Mingming 1; He, Maoshuai 4; Jiang, Hua 5; Zhang, Qiang 6; Xin, Fangyun 1; Tian, Ying 1
通讯作者	Xin, Fangyun(xin_2020@dlmu.edu.cn) ; Tian, Ying(tianying@dlmu.edu.cn)
	2023-12-15
发表期刊	SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
ISSN	1386-1425
卷号	303 页码:8
摘要	Conventional photothermal therapy (PTT) usually relies on a macroscopic heat source to raise the temperature of tissues to 41-45 degrees C, which not only kills the pathological cells but causes severe side effects on nearby normal tissues, thus reducing the accuracy of PTT. Here we successfully fabricated nanocomposites of NaYF4:Yb3+, Tm3+@NaYF4:Yb3+@SiO2-SWCNTs, in which the upconversion nanoparticles (UCNPs) serve as real-time temperature-feedback moiety and the single-walled carbon nanotubes (SWCNTs) serve as efficient nano-heaters. The sample displays an excellent photothermal conversion capacity, i.e., the temperature of the aqueous dispersion increases from 23.3 degrees C up to 60.1 degrees C under 980 nm excitation due to the intense absorption and highly efficient heat generation of SWCNTs. Meanwhile, the temperature of the nanocomposites is monitored in real time based on the fluorescent intensity ratio of UCNPs. The in-vitro experiments demonstrate that the temperature of the nanocomposites at tissue injection of 1 mm can reach PTT temperature of 42.2 degrees C with a facile surrounding temperature of 36.2 degrees C under moderate laser power (980 nm, 2.0 W cm-2). These results provide a novel design for multifunctional nanocomposites that enable safe and controlled PTT.
关键词	Upconversion nanoparticles Single -walled carbon nanotubes Nanocomposite Hyperthermia Temperature sensing
资助者	National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities
DOI	10.1016/j.saa.2023.123173
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[11504039] ; National Natural Science Foundation of China[3132023193] ; Fundamental Research Funds for the Central Universities ; [12004063]
WOS研究方向	Spectroscopy
WOS类目	Spectroscopy
WOS记录号	WOS:001058572300001
出版者	PERGAMON-ELSEVIER SCIENCE LTD
引用统计	被引频次：3[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/179000
专题	中国科学院金属研究所
通讯作者	Xin, Fangyun; Tian, Ying
作者单位	1.Dalian Maritime Univ, Sch Sci, Dalian 116026, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Shenyang 110016, Peoples R China 3.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 230026, Peoples R China 4.Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China 5.Aalto Univ, Sch Sci, Dept Appl Phys, Puumiehenkuja 2, Aalto 00076, Finland 6.Honda Res Inst Inc, 70 Rio Robles, San Jose, CA 95134 USA
推荐引用方式 GB/T 7714	Xu, Yang,Zou, Mengke,Wang, Hong,et al. Upconversion nanoparticles@single-walled carbon nanotubes composites as efficient self-monitored photo-thermal agents[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2023,303:8.
APA	Xu, Yang.,Zou, Mengke.,Wang, Hong.,Zhang, Lili.,Xing, Mingming.,...&Tian, Ying.(2023).Upconversion nanoparticles@single-walled carbon nanotubes composites as efficient self-monitored photo-thermal agents.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,303,8.
MLA	Xu, Yang,et al."Upconversion nanoparticles@single-walled carbon nanotubes composites as efficient self-monitored photo-thermal agents".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 303(2023):8.