Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats

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	Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats
	Y. Guo; L. Ren; C. Liu; Y. J. Yuan; X. Lin; L. L. Tan; S. R. Chen; K. Yang; X. F. Mei
	2013
发表期刊	Materials Science & Engineering C-Materials for Biological Applications
ISSN	0928-4931
卷号	33 期号:7 页码:4470-4474
摘要	The study was focused on the implantation of a biodegradable AZ31 magnesium alloy into the femoral periosteal of the osteoporosis modeled rats. The experimental results showed that after 4 weeks implantation of AZ31 alloy in the osteoporosis modeled rats, the expression of BMP-2 in bone tissues of the rats was much enhanced, even higher than the control group, which should promote the bone formation and be beneficial for reducing the harmful effect of osteoporosis. Results of HE stains showed that the implantation of AZ31 alloy did not have obvious pathological changes on both the liver and kidney of the animal. (C) 2013 Elsevier B.V. All rights reserved.
部门归属	[guo, yue ; liu, chang ; yuan, yajiang ; chen, shurui ; mei, xifan] liaoning med univ, jinzhou 121000, peoples r china. [ren, ling ; lin, xiao ; tan, lili ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. ; yang, k (reprint author), chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china. ; 373073766@qq.com ; lren@imr.ac.cn ; meixifan1971@163.com ; yuan925@163.com ; linx@imr.ac.cn ; lltan@imr.ac.cn ; 272146792@qq.com ; kyang@imr.ac.cn ; meixifan1971@163.com
关键词	Magnesium Alloy Bmp-2 Osteoporosis Osteoblast Differentiation
URL	查看原文
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/71240
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	Y. Guo,L. Ren,C. Liu,et al. Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats[J]. Materials Science & Engineering C-Materials for Biological Applications,2013,33(7):4470-4474.
APA	Y. Guo.,L. Ren.,C. Liu.,Y. J. Yuan.,X. Lin.,...&X. F. Mei.(2013).Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats.Materials Science & Engineering C-Materials for Biological Applications,33(7),4470-4474.
MLA	Y. Guo,et al."Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats".Materials Science & Engineering C-Materials for Biological Applications 33.7(2013):4470-4474.