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In vitro degradation and biocompatibility of a strontium-containing micro-arc oxidation coating on the biodegradable ZK60 magnesium alloy
X. Lin; X. M. Yang; L. L. Tan; M. Li; X. Wang; Y. Zhang; K. Yang; Z. Q. Hu; J. H. Qiu
2013
Source PublicationApplied Surface Science
ISSN0169-4332
Volume288Pages:718-726
AbstractMagnesium alloys are promising biodegradable implant candidates for orthopedic application. In the present study, a phosphate-based micro-arc oxidation (MAO) coating was applied on the ZK60 alloy to decrease its initial degradation rate. Strontium (Sr) was incorporated into the coating in order to improve the bioactivity of the coating. The in vitro degradation studies showed that the MAO coating containing Sr owned a better initial corrosion resistance, which was mainly attributed to the superior inner barrier layer, and a better long-term protective ability, probably owning to its larger thickness, superior inner barrier layer and the superior apatite formation ability. The degradation of MAO coating was accompanied by the formation of degradation layer and Ca-P deposition layer. The in vitro cell tests demonstrated that the incorporation of Sr into the MAO coating enhanced both the proliferation of preosteoblast cells and the alkaline phosphatase activity of the murine bone marrow stromal cells. In conclusion, the MAO coating with Sr is a promising surface treatment for the biodegradable magnesium alloys. (C) 2013 Elsevier B. V. All rights reserved.
description.department[lin, xiao ; tan, lili ; yang, ke ; hu, zhuangqi] chinese acad sci, inst met res, shenyang 110016, peoples r china. [yang, xiaoming] panyu hosp chinese med, guangzhou 511400, guangdong, peoples r china. [li, mei ; zhang, yu] guangzhou mil command, guangzhou gen hosp, hosp orthoped, guangzhou 510010, guangdong, peoples r china. [wang, xin] liaoning univ, coll chem, shenyang 110036, peoples r china. [qiu, jianhong] trauson med instrument co ltd, changzhou 213163, peoples r china. ; tan, ll (reprint author), chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china. ; lltan@imr.ac.cn ; luck_2001@126.com ; kyang@imr.ac.cn
KeywordBiodegradation Micro-arc Oxidation Biocompatibility Biodegradable Magnesium Strontium Plasma Electrolytic Oxidation Simulated Body-fluid Vivo Degradation Sr Alloys Mg-sr Corrosion Behavior Implant Materials Bone Resorption Hydroxyapatite
URL查看原文
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/71352
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
X. Lin,X. M. Yang,L. L. Tan,et al. In vitro degradation and biocompatibility of a strontium-containing micro-arc oxidation coating on the biodegradable ZK60 magnesium alloy[J]. Applied Surface Science,2013,288:718-726.
APA X. Lin.,X. M. Yang.,L. L. Tan.,M. Li.,X. Wang.,...&J. H. Qiu.(2013).In vitro degradation and biocompatibility of a strontium-containing micro-arc oxidation coating on the biodegradable ZK60 magnesium alloy.Applied Surface Science,288,718-726.
MLA X. Lin,et al."In vitro degradation and biocompatibility of a strontium-containing micro-arc oxidation coating on the biodegradable ZK60 magnesium alloy".Applied Surface Science 288(2013):718-726.
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