| Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy |
| Z.; Yao Ma, M.; Liu, R.; Yang, K.; Ren, L.; Zhang, Y.; Liao, Z.; Liu, W.; Qi, M.
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| 2015
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| 发表期刊 | Materials Technology
 |
| ISSN | 1066-7857
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| 卷号 | 30期号:B2页码:B80-B85 |
| 摘要 | A new biomedical Ti-6Al-4V-5Cu alloy with antibacterial function was developed by proper addition of copper (Cu) into Ti based alloy in this study. The microstructure, antibacterial activity and cytotoxicity of this Cu bearing titanium alloy were studied. It was found that the microstructure of Ti-6Al-4V-5Cu alloy consisted of alpha phase, beta phase and Ti2Cu intermetallic compound, which could obtain a considerable antibacterial ability and inhibit the formation of bacterial biofilm through trace release of cupric ions from its surface. The cytotoxicity evaluation demonstrated that Ti-6Al-4V alloy played no toxic effect on the viability of MC3T3-E1 cells, showing a satisfied biocompatibility. |
| 部门归属 | [ma, z.
; qi, m.] dalian univ technol, sch mat sci & engn, dalian, peoples r china. [ma, z.
; liu, r.
; yang, k.
; ren, l.] chinese acad sci, inst met res, shenyang 110016, peoples r china. [yao, m.] second mil med univ, shanghai, peoples r china. [yao, m.
; zhang, y.] guangzhou mil gen hosp, dept orthoped, guangzhou, guangdong, peoples r china. [liao, z.
; liu, w.] tsinghua univ, shenzhen res inst, inst med engn, shenzhen 518057, peoples r china.
; ren, l (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china.
; lren@imr.ac.cn
; luck_2001@126.com
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| 关键词 | Ti-6al-4v
Copper
Antibacterial
Biocompatibility
Ti-cu Alloys
Joint Infections
Stainless-steel
Titanium
Nanoparticles
Grindability
Wear
Hip
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| URL | 查看原文
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| 文献类型 | 期刊论文
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| 条目标识符 | http://ir.imr.ac.cn/handle/321006/73886
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| 专题 | 中国科学院金属研究所
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推荐引用方式
GB/T 7714 |
Z.,Yao Ma, M.,Liu, R.,et al. Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy[J]. Materials Technology,2015,30(B2):B80-B85.
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| APA |
Z..,Yao Ma, M..,Liu, R..,Yang, K..,Ren, L..,...&Qi, M..(2015).Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy.Materials Technology,30(B2),B80-B85.
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| MLA |
Z.,et al."Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy".Materials Technology 30.B2(2015):B80-B85.
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