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Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy
Z.; Yao Ma, M.; Liu, R.; Yang, K.; Ren, L.; Zhang, Y.; Liao, Z.; Liu, W.; Qi, M.
2015
Source PublicationMaterials Technology
ISSN1066-7857
Volume30Issue:B2Pages:B80-B85
AbstractA new biomedical Ti-6Al-4V-5Cu alloy with antibacterial function was developed by proper addition of copper (Cu) into Ti based alloy in this study. The microstructure, antibacterial activity and cytotoxicity of this Cu bearing titanium alloy were studied. It was found that the microstructure of Ti-6Al-4V-5Cu alloy consisted of alpha phase, beta phase and Ti2Cu intermetallic compound, which could obtain a considerable antibacterial ability and inhibit the formation of bacterial biofilm through trace release of cupric ions from its surface. The cytotoxicity evaluation demonstrated that Ti-6Al-4V alloy played no toxic effect on the viability of MC3T3-E1 cells, showing a satisfied biocompatibility.
description.department[ma, z. ; qi, m.] dalian univ technol, sch mat sci & engn, dalian, peoples r china. [ma, z. ; liu, r. ; yang, k. ; ren, l.] chinese acad sci, inst met res, shenyang 110016, peoples r china. [yao, m.] second mil med univ, shanghai, peoples r china. [yao, m. ; zhang, y.] guangzhou mil gen hosp, dept orthoped, guangzhou, guangdong, peoples r china. [liao, z. ; liu, w.] tsinghua univ, shenzhen res inst, inst med engn, shenzhen 518057, peoples r china. ; ren, l (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china. ; lren@imr.ac.cn ; luck_2001@126.com
KeywordTi-6al-4v Copper Antibacterial Biocompatibility Ti-cu Alloys Joint Infections Stainless-steel Titanium Nanoparticles Grindability Wear Hip
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Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/73886
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
Z.,Yao Ma, M.,Liu, R.,et al. Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy[J]. Materials Technology,2015,30(B2):B80-B85.
APA Z..,Yao Ma, M..,Liu, R..,Yang, K..,Ren, L..,...&Qi, M..(2015).Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy.Materials Technology,30(B2),B80-B85.
MLA Z.,et al."Study on antibacterial activity and cytocompatibility of Ti-6Al-4V-5Cu alloy".Materials Technology 30.B2(2015):B80-B85.
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