IMR OpenIR
The Effects of SiC Foams on Cell Proliferation and Differentiation in Primary Osteoblasts
L.; Yuan Wu, Y.; Hao, F. Y.; Yang, Z. M.; Zhang, J. S.; Yu, M.
2015
Source PublicationJournal of Hard Tissue Biology
ISSN1341-7649
Volume24Issue:1Pages:37-42
AbstractThe objective of this study was to investigate the possibility of silicon carbide (SiC) foam as an alternative material for porous hydroxyapatite (HA). The characters of two materials were evaluated and compared by a series of in vitro biological tests. The result of the morphology showed that SiC foam provided beneficial structure for cell migration. On the level of primary-osteoblasts proliferation measured by MTT assay and cell cycle analysis showed that the proliferation rate increased in the early stage on HA but in the advanced stage on SiC foam. There was no significant difference between the two materials on the level of cell differentiation detected by alkaline phosphatase (ALP) assay and real-time PCR. All of the results indicated that SiC foam was comparable to HA in terms of biocompatibility and bone conductivity.
description.department[wu, lin ; yuan, yue ; hao, fengyu] china med univ, sch stomatol, dept prosthodont, shenyang 110002, peoples r china. [yang, zhenming ; zhang, jinsong] chinese acad sci, inst met res, mat fabricat & proc div, shenyang 110016, peoples r china. [yu, meng] china med univ, dept lab anim, key lab transgenet anim res, shenyang 110002, liaoning provin, peoples r china. ; wu, l (reprint author), china med univ, sch stomatol, dept prosthodont, 117 nanjing,n st, shenyang 110002, peoples r china. ; wulin13@163.com
KeywordBiocompatibility Osteoblasts Porous Hydroxyapatite Silicon Carbide Foam Silicon-carbide Bone Hydroxyapatite
URL查看原文
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/73974
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
L.,Yuan Wu, Y.,Hao, F. Y.,et al. The Effects of SiC Foams on Cell Proliferation and Differentiation in Primary Osteoblasts[J]. Journal of Hard Tissue Biology,2015,24(1):37-42.
APA L.,Yuan Wu, Y.,Hao, F. Y.,Yang, Z. M.,Zhang, J. S.,&Yu, M..(2015).The Effects of SiC Foams on Cell Proliferation and Differentiation in Primary Osteoblasts.Journal of Hard Tissue Biology,24(1),37-42.
MLA L.,et al."The Effects of SiC Foams on Cell Proliferation and Differentiation in Primary Osteoblasts".Journal of Hard Tissue Biology 24.1(2015):37-42.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[L.]'s Articles
[Yuan Wu, Y.]'s Articles
[Hao, F. Y.]'s Articles
Baidu academic
Similar articles in Baidu academic
[L.]'s Articles
[Yuan Wu, Y.]'s Articles
[Hao, F. Y.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[L.]'s Articles
[Yuan Wu, Y.]'s Articles
[Hao, F. Y.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.