Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy

IMR OpenIR

	Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy
	Ma, Zheng; Ren, Ling; Liu, Rui; Yang, Ke; Zhang, Yu; Liao, Zhenhua; Liu, Weiqiang; Qi, Min; Misra, R. D. K.; kyang@imr.ac.cn
	2015
发表期刊	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN	1005-0302
卷号	31 期号:7 页码:723-732
摘要	A copper-bearing Ti-6Al-4V-5Cu alloy was processed and subjected to different heat treatments to explore the relationship among microstructure, antibacterial performance, and cytocompatibility. Characterization of microstructure revealed that the solution treated alloy consisted of alpha phase, alpha' phase and beta phase, while besides these phases, the aged alloy also contained the precipitations of intermetallic Ti2Cu compound. The solution treated alloy showed better antibacterial performance with increasing the solution temperature. The Cu ions released from Ti-6Al-4V-5Cu alloy could effectively inhibit the formation of bacterial biofilm on the surface of alloy, and do not induce any cytotoxicity. The optimal heat treatment for Ti-6Al-4V-5Cu alloy was solution treated at 930 degrees C, at which it could exhibit both promising antibacterial performance and no cytotoxicity. Copyright (C) 2015, The editorial office of Journal of Materials Science & Technology. Published by Elsevier Limited. All rights reserved.
部门归属	[ma, zheng ; ren, ling ; liu, rui ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china ; [ma, zheng ; qi, min] dalian univ technol, sch mat sci & engn, dalian 116024, peoples r china ; [zhang, yu] guangzhou mil gen hosp, dept orthoped, guangzhou 510010, guangdong, peoples r china ; [liao, zhenhua ; liu, weiqiang] qinghua univ, shenzhen res inst, inst med engn, shenzhen 518057, peoples r china ; [misra, r. d. k.] univ texas el paso, dept met & mat engn, el paso, tx 79968 usa
关键词	Ti-6al-4v-5cu Heat Treatment Microstructure Antibacterial Performance Cytocompatibility
资助者	National Basic Research Program of China [2012CB619101]; National Natural Science Foundation of China [81271957]; Basic Research Project of Shenzhen City [JCYJ20120616142847342]
收录类别	sci
语种	英语
WOS记录号	WOS:000356606700004
引用统计	被引频次：131[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/74751
专题	中国科学院金属研究所
通讯作者	kyang@imr.ac.cn
推荐引用方式 GB/T 7714	Ma, Zheng,Ren, Ling,Liu, Rui,et al. Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2015,31(7):723-732.
APA	Ma, Zheng.,Ren, Ling.,Liu, Rui.,Yang, Ke.,Zhang, Yu.,...&kyang@imr.ac.cn.(2015).Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,31(7),723-732.
MLA	Ma, Zheng,et al."Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 31.7(2015):723-732.