Antimicrobial Cu-bearing stainless steel scaffolds

IMR OpenIR

	Antimicrobial Cu-bearing stainless steel scaffolds
	Wang, Q; Ren, L; Li, XP; Zhang, SY; Sercombe, TB; Yang, K; Wang, Q (reprint author), China Med Univ, Sch Stomatol, Shenyang 110002, Peoples R China.; Yang, K (reprint author), Chinese Acad Sci, Inst Met Res, Beijing 100864, Peoples R China.; Sercombe, TB (reprint author), Univ Western Australia, Sch Mech & Chem Engn, Nedlands, WA 6009, Australia.
	2016-11-01
发表期刊	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
ISSN	0928-4931
卷号	68 页码:519-522
摘要	Copper-bearing stainless steel scaffolds with two different structures (Body Centered Cubic and Gyroid labyrinth) at two solid fractions (25% and 40%) were fabricated from both 316L powder and a mixture of 316L and elemental Cu powder using selective laser melting, and relative 316L scaffolds were served as control group. After processing, the antimicrobial testing demonstrated that the 316L-Cu scaffolds presented excellent antimicrobial activity against Escherichia coli and Staphylococcus aureus, and the cell viability assay indicated that there was no cytotoxic effect of 316L-Cu scaffolds on rat marrow mesenchymal stem cells. As such, these have the potential to reduce implant-associated infections. The Cu was also found to homogeneously distribute within the microstructure by scanning electronic microcopy. The addition of Cu would not significantly affect its strength and stiffness compared to 316L scaffold, and the stiffness of all the scaffolds (3-20GPa) is similar to that of bone and much less than that of bulk stainless steel. Consequently, fabrication of such low stiffness porous structures, especially coupled with the addition of antimicrobial Cu, may provide a new direction for medical stainless steels. (C) 2016 Elsevier B.V. All rights reserved.
部门归属	[wang, qiang] china med univ, sch stomatol, shenyang 110002, peoples r china ; [ren, ling ; zhang, shuyuan ; yang, ke] chinese acad sci, inst met res, beijing 100864, peoples r china ; [li, xiaopeng ; sercombe, timothy b.] univ western australia, sch mech & chem engn, nedlands, wa 6009, australia
学科领域	Materials Science, bioMaterials
资助者	National Natural Science Foundation [81301329]; Youth Innovation Promotion Association, CAS [2014168]; Liaoning Province Natural Science Foundation [2015021004]; Shenyang National Laboratory for Materials Science [2015021004]
收录类别	sci
语种	英语
WOS记录号	WOS:000382600000061
引用统计	被引频次：44[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/76220
专题	中国科学院金属研究所
通讯作者	Wang, Q (reprint author), China Med Univ, Sch Stomatol, Shenyang 110002, Peoples R China.; Yang, K (reprint author), Chinese Acad Sci, Inst Met Res, Beijing 100864, Peoples R China.; Sercombe, TB (reprint author), Univ Western Australia, Sch Mech & Chem Engn, Nedlands, WA 6009, Australia.
推荐引用方式 GB/T 7714	Wang, Q,Ren, L,Li, XP,et al. Antimicrobial Cu-bearing stainless steel scaffolds[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2016,68:519-522.
APA	Wang, Q.,Ren, L.,Li, XP.,Zhang, SY.,Sercombe, TB.,...&Sercombe, TB .(2016).Antimicrobial Cu-bearing stainless steel scaffolds.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,68,519-522.
MLA	Wang, Q,et al."Antimicrobial Cu-bearing stainless steel scaffolds".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 68(2016):519-522.