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Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth
Wang, R; Zhu, PF; Yang, WY; Gao, S; Li, B; Li, Q; Li, Q (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Environm Funct Mat Div, Shenyang 110016, Liaoning, Peoples R China.
2018-04-15
Source PublicationMATERIALS & DESIGN
ISSN0264-1275
Volume144Pages:304-309
AbstractIn this work, three-dimensional (3D) periodic TiO2 bio-ceramic scaffolds were created by continuous filament writing with TiO2 sol-gel ink followed by sintering. The TiO2 sol-gel ink has the advantage of creating 3D bio-ceramic scaffolds with finer feature size than commonly used ceramic powder based ink systems. The structure, pore sizes, and interconnectivity could be controlled through 3D structure design and printing parameter adjustment. To evaluate the potential of these 3D TiO2 bio-ceramic scaffolds for bone tissue engineering, the mouse osteoblastic cell line MC3T3-E1 was cultured on them. The observed good viability demonstrated that 3D TiO2 bio-ceramic scaffolds created by direct-writing technique provide a biocompatible environment that favors cell growth and attachment. (C) 2018 Elsevier Ltd. All rights reserved.; In this work, three-dimensional (3D) periodic TiO2 bio-ceramic scaffolds were created by continuous filament writing with TiO2 sol-gel ink followed by sintering. The TiO2 sol-gel ink has the advantage of creating 3D bio-ceramic scaffolds with finer feature size than commonly used ceramic powder based ink systems. The structure, pore sizes, and interconnectivity could be controlled through 3D structure design and printing parameter adjustment. To evaluate the potential of these 3D TiO2 bio-ceramic scaffolds for bone tissue engineering, the mouse osteoblastic cell line MC3T3-E1 was cultured on them. The observed good viability demonstrated that 3D TiO2 bio-ceramic scaffolds created by direct-writing technique provide a biocompatible environment that favors cell growth and attachment. (C) 2018 Elsevier Ltd. All rights reserved.
description.department[wang, rong ; zhu, pengfei ; yang, weiyi ; li, qi] chinese acad sci, inst met res, shenyang natl lab mat sci, environm funct mat div, shenyang 110016, liaoning, peoples r china ; [wang, rong] univ chinese acad sci, beijing 100049, peoples r china ; [zhu, pengfei] univ sci & technol china, sch mat sci & engn, shenyang 110016, liaoning, peoples r china ; [gao, shuang ; li, bo] tsinghua univ, grad sch shenzhen, div energy & environm, shenzhen 518055, peoples r china
KeywordEmbryonic Stem-cells Bone Scaffolds Hydrogel Scaffolds Culture-systems Silk Fibroin Titanium 2d Regeneration Osteogenesis
Subject AreaMaterials Science, Multidisciplinary
Funding OrganizationShenyang National Laboratory for Materials Science [Y4N56R1161, Y4N56F2161]; National Natural Science Foundation of China [51672283, 51602316]; Science and Technology Plan of Shenzhen City [JCYJ20150827165038323, JCYJ20160301154309393]
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/79360
Collection中国科学院金属研究所
Corresponding AuthorLi, Q (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Environm Funct Mat Div, Shenyang 110016, Liaoning, Peoples R China.
Recommended Citation
GB/T 7714
Wang, R,Zhu, PF,Yang, WY,et al. Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth[J]. MATERIALS & DESIGN,2018,144:304-309.
APA Wang, R.,Zhu, PF.,Yang, WY.,Gao, S.,Li, B.,...&Li, Q .(2018).Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth.MATERIALS & DESIGN,144,304-309.
MLA Wang, R,et al."Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth".MATERIALS & DESIGN 144(2018):304-309.
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