Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth

IMR OpenIR

	Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth
	Wang, R; Zhu, PF; Yang, WY; Gao, S; Li, B; Li, Q; Li, Q (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Environm Funct Mat Div, Shenyang 110016, Liaoning, Peoples R China.
	2018-04-15
发表期刊	MATERIALS & DESIGN
ISSN	0264-1275
卷号	144 页码:304-309
摘要	In this work, three-dimensional (3D) periodic TiO2 bio-ceramic scaffolds were created by continuous filament writing with TiO2 sol-gel ink followed by sintering. The TiO2 sol-gel ink has the advantage of creating 3D bio-ceramic scaffolds with finer feature size than commonly used ceramic powder based ink systems. The structure, pore sizes, and interconnectivity could be controlled through 3D structure design and printing parameter adjustment. To evaluate the potential of these 3D TiO2 bio-ceramic scaffolds for bone tissue engineering, the mouse osteoblastic cell line MC3T3-E1 was cultured on them. The observed good viability demonstrated that 3D TiO2 bio-ceramic scaffolds created by direct-writing technique provide a biocompatible environment that favors cell growth and attachment. (C) 2018 Elsevier Ltd. All rights reserved.; In this work, three-dimensional (3D) periodic TiO2 bio-ceramic scaffolds were created by continuous filament writing with TiO2 sol-gel ink followed by sintering. The TiO2 sol-gel ink has the advantage of creating 3D bio-ceramic scaffolds with finer feature size than commonly used ceramic powder based ink systems. The structure, pore sizes, and interconnectivity could be controlled through 3D structure design and printing parameter adjustment. To evaluate the potential of these 3D TiO2 bio-ceramic scaffolds for bone tissue engineering, the mouse osteoblastic cell line MC3T3-E1 was cultured on them. The observed good viability demonstrated that 3D TiO2 bio-ceramic scaffolds created by direct-writing technique provide a biocompatible environment that favors cell growth and attachment. (C) 2018 Elsevier Ltd. All rights reserved.
部门归属	[wang, rong ; zhu, pengfei ; yang, weiyi ; li, qi] chinese acad sci, inst met res, shenyang natl lab mat sci, environm funct mat div, shenyang 110016, liaoning, peoples r china ; [wang, rong] univ chinese acad sci, beijing 100049, peoples r china ; [zhu, pengfei] univ sci & technol china, sch mat sci & engn, shenyang 110016, liaoning, peoples r china ; [gao, shuang ; li, bo] tsinghua univ, grad sch shenzhen, div energy & environm, shenzhen 518055, peoples r china
关键词	Embryonic Stem-cells Bone Scaffolds Hydrogel Scaffolds Culture-systems Silk Fibroin Titanium 2d Regeneration Osteogenesis
学科领域	Materials Science, Multidisciplinary
资助者	Shenyang National Laboratory for Materials Science [Y4N56R1161, Y4N56F2161]; National Natural Science Foundation of China [51672283, 51602316]; Science and Technology Plan of Shenzhen City [JCYJ20150827165038323, JCYJ20160301154309393]
收录类别	SCI
语种	英语
WOS记录号	WOS:000427609400028
引用统计	被引频次：30[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/79360
专题	中国科学院金属研究所
通讯作者	Li, Q (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Environm Funct Mat Div, Shenyang 110016, Liaoning, Peoples R China.
推荐引用方式 GB/T 7714	Wang, R,Zhu, PF,Yang, WY,et al. Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth[J]. MATERIALS & DESIGN,2018,144:304-309.
APA	Wang, R.,Zhu, PF.,Yang, WY.,Gao, S.,Li, B.,...&Li, Q .(2018).Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth.MATERIALS & DESIGN,144,304-309.
MLA	Wang, R,et al."Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth".MATERIALS & DESIGN 144(2018):304-309.