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Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707
作者:  Liu Tongchao;  Peng Xia;  Ma Yuchi;  Ji Yinchun;  Chen Danqi;  Zheng Mingyue;  Zhao Dongmei;  Cheng Maosheng;  Geng Meiyu;  Shen Jingkang;  Ai Jing;  Xiong Bing
收藏  |  浏览/下载：156/0  |  提交时间：2021/02/02
RECEPTOR TYROSINE KINASE  INVASIVE GROWTH  SCATTER FACTOR  CANCER  DOCKING  c-Met inhibitors  hepatocyte growth factor receptor  imidazo1,2-apyridine  anticancer agents  drug discovery  
Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707
作者:  Liu Tongchao;  Peng Xia;  Ma Yuchi;  Ji Yinchun;  Chen Danqi;  Zheng Mingyue;  Zhao Dongmei;  Cheng Maosheng;  Geng Meiyu;  Shen Jingkang;  Ai Jing;  Xiong Bing
收藏  |  浏览/下载：133/0  |  提交时间：2021/02/02
RECEPTOR TYROSINE KINASE  INVASIVE GROWTH  SCATTER FACTOR  CANCER  DOCKING  c-Met inhibitors  hepatocyte growth factor receptor  imidazo1,2-apyridine  anticancer agents  drug discovery  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
作者:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
收藏  |  浏览/下载：103/0  |  提交时间：2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
作者:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
收藏  |  浏览/下载：179/0  |  提交时间：2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
In vitro assay of cytoskeleton nanomechanics as a tool for screening potential anticancer effects of natural plant extract, tubeimoside I on human hepatoma (HepG2) cells 期刊论文
CHINESE SCIENCE BULLETIN, 2013, 卷号: 58, 期号: 21, 页码: 2576-2583
作者:  Zhao HongBo;  Wang YaShu;  Jiang XueMei;  Shi XiaoHao;  Zhong HongZhe;  Wang YaJie;  Chen Jun;  Deng LinHong
收藏  |  浏览/下载：102/0  |  提交时间：2021/02/02
MUSCLE CELLS  ACTIN  CYTOTOXICITY  APOPTOSIS  HepG2 cells  F-actin cytoskeleton  nanomechanics  tubeimoside I  anticancer drug screening  
In vitro assay of cytoskeleton nanomechanics as a tool for screening potential anticancer effects of natural plant extract, tubeimoside I on human hepatoma (HepG2) cells 期刊论文
CHINESE SCIENCE BULLETIN, 2013, 卷号: 58, 期号: 21, 页码: 2576-2583
作者:  Zhao HongBo;  Wang YaShu;  Jiang XueMei;  Shi XiaoHao;  Zhong HongZhe;  Wang YaJie;  Chen Jun;  Deng LinHong
收藏  |  浏览/下载：115/0  |  提交时间：2021/02/02
MUSCLE CELLS  ACTIN  CYTOTOXICITY  APOPTOSIS  HepG2 cells  F-actin cytoskeleton  nanomechanics  tubeimoside I  anticancer drug screening  
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule 期刊论文
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 2, 页码: 261-270
作者:  Liu Zulong;  Tian Wei;  Wang Yong;  Kuang Shan;  Luo Xiaomin;  Yu Qiang
收藏  |  浏览/下载：119/0  |  提交时间：2021/02/02
PHASE-I  ANTITUMOR-ACTIVITY  ANTICANCER AGENT  BINDING  APOPTOSIS  E7070  COLCHICINE  DISCOVERY  HMN-214  CAMPTOTHECIN  MPSP-001  sulfonamide  anticancer drug  microtubules  tubulin  mitotic spindle  drug resistance  drug synergism