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Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
作者:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
收藏  |  浏览/下载：99/0  |  提交时间：2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
作者:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
收藏  |  浏览/下载：173/0  |  提交时间：2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
Adenosine triphosphate-sensitive potassium channel opener protects PC12 cells against hypoxia-induced apoptosis through PI3K/Akt and Bcl-2 signaling pathways 期刊论文
NEURAL REGENERATION RESEARCH, 2010, 卷号: 5, 期号: 22, 页码: 1706-1711
作者:  Zhang Hong;  Jia Chunhong;  Zhao Danyang;  Lu Yang;  Wang Runling;  Li Jia
收藏  |  浏览/下载：106/0  |  提交时间：2021/02/02
BRAIN  ISCHEMIA  AKT  NEUROPROTECTION  EXPRESSION  SURVIVAL  DEATH  ATP-sensitive potassium channel  PC12 cells  hypoxia  apoptosis  pinacidil  phosphatidylinositol-3 kinase/v-akt murine thymoma viral oncogene homolog  Bcl-2  
Apelin protects against cardiomyocyte apoptosis induced by glucose deprivation 期刊论文
CHINESE MEDICAL JOURNAL, 2009, 卷号: 122, 期号: 19, 页码: 2360-2365
作者:  Zhang Zhi;  Yu Bo;  Tao Guizhou
收藏  |  浏览/下载：128/0  |  提交时间：2021/02/02
ISCHEMIC-HEART FAILURE  REPERFUSION INJURY  APJ RECEPTOR  CONTRACTILITY  LOCALIZATION  EXPRESSION  AUTOPHAGY  SURVIVAL  SALVAGE  SYSTEM  apelin  apoptosis  cardiomyocyte  phosphatidylinositol 3-OH kinase (PI3K)/Akt  
Alisol B acetate induces apoptosis of SGC7901 cells via mitochondrial and phosphatidylinositol 3-kinases/Akt signaling pathways 期刊论文
WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 卷号: 15, 期号: 23, 页码: 2870-2877
作者:  Xu YongHong;  Zhao LiJie;  Li Yan
收藏  |  浏览/下载：84/0  |  提交时间：2021/02/02
RHIZOMA DRIED RHIZOME  PROTEIN-KINASE-B  PROSTATE-CANCER  ALISMATIS-RHIZOMA  BCL-2 FAMILY  TERPENE COMPONENTS  METHANOL EXTRACT  AKT  ORIENTALE  SURVIVAL  Alisol B acetate  Apoptosis  Mitochondria  Phosphatidylinositol 3-kinases/Akt  SGC7901 cells  
Roles of PI3-K/Akt pathways in nanoparticle realgar powders-induced apoptosis in U937 cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 3, 页码: 355-363
作者:  Xi Ronggang;  Huang Jian;  Li Dan;  Wang Xiaobo;  Wu Lijun
收藏  |  浏览/下载：166/0  |  提交时间：2021/02/02
SIGNAL-REGULATED KINASE  A375-S2 CELLS  CYTOCHROME-C  HELA-CELLS  P53  ACTIVATION  CANCER  MDM2  DEGRADATION  INHIBITION  nanoparticle realgar powders  apoptosis  caspase-3  phosphoinositide 3-kinase  Akt  a nicotinamide adenine dinucleotide (NAD(+))-dependent histone deacetylase (SIRT1)  p53