A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides

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	A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides
其他题名	A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides
	Zhao HaiLong 1; Zhou Jie 1; Song HongRui 3; Xu BaiLing 1
	2014
发表期刊	CHINESE CHEMICAL LETTERS
ISSN	1001-8417
卷号	25 期号:3 页码:411-414
摘要	A facile and efficient protocol was developed to access 2-alkoxy-4-amino-N-aryithiazole-5-carboxamides through a three-component one-pot reaction, which involved potassium methyl cyanimidodithiocarbonate, 2-halo-N-arylacetamides and alcohols. The easy availability and the broad structural diversity of substrates make the reaction useful for the construction of libraries in drug discovery. (C) 2013 Bai-Ling Xu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
其他摘要	A facile and efficient protocol was developed to access 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides through a three-component one-pot reaction, which involved potassium methyl cyanimidodithiocarbonate, 2-halo-N-arylacetamides and alcohols. The easy availability and the broad structural diversity of substrates make the reaction useful for the construction of libraries in drug discovery.
关键词	HUMAN PIN1 INHIBITORS BIOLOGICAL EVALUATION DERIVATIVES AGENTS 4-Aminothiazole-5-carboxamide Potassium methyl cyanimidodithiocarbonate Acetamide
收录类别	CSCD
语种	英语
资助项目	[National Natural Science Foundation of China] ; ["863" Program of China]
CSCD记录号	CSCD:5069001
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/142703
专题	中国科学院金属研究所
作者单位	1.Chinese Acad Med Sci, Institute Mat Med, Beijing Key Lab Act Subst Discovery & Drug Evalua, Beijing 100050, Peoples R China Institute Mat Med Beijing Key Lab Act Subst Discovery & Drug Evalua 2.Peking Union Med Coll, Beijing 100050, Peoples R China 3.中国科学院金属研究所
推荐引用方式 GB/T 7714	Zhao HaiLong,Zhou Jie,Song HongRui,et al. A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides[J]. CHINESE CHEMICAL LETTERS,2014,25(3):411-414.
APA	Zhao HaiLong,Zhou Jie,Song HongRui,&Xu BaiLing.(2014).A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides.CHINESE CHEMICAL LETTERS,25(3),411-414.
MLA	Zhao HaiLong,et al."A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides".CHINESE CHEMICAL LETTERS 25.3(2014):411-414.