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Nasal mucosal inhalation of amyloid-beta peptide 3-10 defective adenovirus attenuates cytotoxicity induced by beta-amyloid (1-42) 期刊论文
NEURAL REGENERATION RESEARCH, 2014, 卷号: 9, 期号: 8, 页码: 872-877
Authors:  Jiang Tongzi;  Guo Wanshu;  Sha Sha;  Xing Xiaona;  Guo Rong;  Cao Yunpeng
Favorite  |  View/Download:42/0  |  Submit date:2021/02/02
ALZHEIMERS-DISEASE  TRANSGENIC MICE  TANDEM REPEATS  MOUSE MODEL  IMMUNIZATION  VACCINATION  MEMORY  IMMUNOTHERAPY  ANTIBODIES  DECLINE  nerve regeneration  neurodegenerative disease  Alzheimer's disease  immunotherapy  amyloid-beta peptide vaccine  cytokines  humoral immunity  inflammation  NSFC grant  neural regeneration  
Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621
Authors:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu;  Tang Jordan
Favorite  |  View/Download:36/0  |  Submit date:2021/02/02
AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction  
Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621
Authors:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu;  Tang Jordan
Favorite  |  View/Download:33/0  |  Submit date:2021/02/02
AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction  
Design, synthesis characterization and in vitro biological activity of a series of 3-aryl-6-(bromoarylmethyl)-7H-thiazolo3,2-b-1, 2, 4-triazin-7-one derivatives as the novel acetylcholinesterase inhibitors 期刊论文
CHINESE CHEMICAL LETTERS, 2012, 卷号: 23, 期号: 7, 页码: 765-768
Authors:  Xu He Nan;  Jin Zhe;  Liu Si Jie;  Liu Hong Min;  Li Shuo;  Lin Huang Quan;  Wan David Chicheong;  Hu Chun
Favorite  |  View/Download:50/0  |  Submit date:2021/02/26
ALZHEIMERS-DISEASE  Acetylcholinesterase inhibitor  Bromination  Heterocycle  Synthesis  7H-Thiazolo3,2-b-1, 2, 4-triazin-7-one derivatives  
Altered regional homogeneity in post-traumatic stress disorder: a restingstate functional magnetic resonance imaging study 期刊论文
NEUROSCIENCE BULLETIN, 2012, 卷号: 28, 期号: 5, 页码: 541-549
Authors:  Yin Yan;  Jin Changfeng;  Eyler Lisa T;  Jin Hua;  Hu Xiaolei;  Duan Lian;  Zheng Huirong;  Feng Bo;  Huang Xuanyin;  Shan Baoci;  Gong Qiyong;  Li Lingjiang
Favorite  |  View/Download:45/0  |  Submit date:2021/02/26
POSITRON-EMISSION-TOMOGRAPHY  VIETNAM COMBAT VETERANS  CHILDHOOD SEXUAL-ABUSE  CEREBRAL-BLOOD-FLOW  STATE FMRI  NETWORK CONNECTIVITY  ALZHEIMERS-DISEASE  MAJOR DEPRESSION  BRAIN-FUNCTION  MEMORY  functional magnetic resonance imaging  post-traumatic stress disorder  regional homogeneity  resting-state  
Neural cell injury microenvironment induces neural differentiation of human umbilical cord mesenchymal stem cells 期刊论文
NEURAL REGENERATION RESEARCH, 2012, 卷号: 7, 期号: 34, 页码: 2689-2697
Authors:  Zhou Jin;  Tian Guoping;  Wang Jinge;  Luo Xiaoguang;  Zhang Siyang;  Li Jianping;  Li Li;  Xu Bing;  Zhu Feng;  Wang Xia;  Jia Chunhong;  Zhao Weijin;  Zhao Danyang;  Xu Aihua
Favorite  |  View/Download:33/0  |  Submit date:2021/02/26
BETA-AMYLOID NEUROTOXICITY  ALZHEIMERS-DISEASE  CHOLINE-ACETYLTRANSFERASE  RAT MODEL  IN-VITRO  REGENERATIVE MEDICINE  HIPPOCAMPAL-NEURONS  COGNITIVE FUNCTION  SCHWANN-CELLS  BONE-MARROW  stem cell  umbilical cord mesenchymal stem cell  co-culture  induction  differentiation  neural cell  microtubule-associated protein 2  injured cell  Transwell  neural regeneration  regeneration  
Induced Th2 dominant immune response in APPswe, PSEN1dE9 transgenic mice after nasal immunization with an adenoviral vector encoding 10 tandem repeats of beta-amyloid 3-10 期刊论文
NEURAL REGENERATION RESEARCH, 2011, 卷号: 6, 期号: 26, 页码: 2005-2012
Authors:  Guo Rong;  Huang Kui;  Jiang Tongzi;  Li Jian;  Li Yu;  Xing Xiaona;  Cao Yunpeng
Favorite  |  View/Download:27/0  |  Submit date:2021/02/26
ALZHEIMERS-DISEASE  MOUSE MODEL  FOLLOW-UP  PEPTIDE  NEUROPATHOLOGY  A-BETA-1-40/42  VACCINATION  IMMUNOGENS  PATHOLOGY  PROTEIN  Alzheimer's disease  immunotherapy  gene vaccine  amyloid plaque  T cell immunity response  neural regeneration  
Changes in intracellular calcium in brain cells of aged rats 期刊论文
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 9, 页码: 1026-1029
Authors:  Li Yu;  Cao Yunpeng
Favorite  |  View/Download:31/0  |  Submit date:2021/02/02
HIPPOCAMPAL CA1 NEURONS  SYNAPTIC PLASTICITY  ALZHEIMERS-DISEASE  SLOW AFTERHYPERPOLARIZATION  ENDOPLASMIC-RETICULUM  PYRAMIDAL NEURONS  AMYLOID-BETA  ESTROGEN  CA2+  DYSREGULATION  aged rats  neuron  intracellular calcium  
Changes in intracellular calcium in brain cells of aged rats 期刊论文
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 9, 页码: 1026-1029
Authors:  Li Yu;  Cao Yunpeng
Favorite  |  View/Download:30/0  |  Submit date:2021/02/02
HIPPOCAMPAL CA1 NEURONS  SYNAPTIC PLASTICITY  ALZHEIMERS-DISEASE  SLOW AFTERHYPERPOLARIZATION  ENDOPLASMIC-RETICULUM  PYRAMIDAL NEURONS  AMYLOID-BETA  ESTROGEN  CA2+  DYSREGULATION  aged rats  neuron  intracellular calcium