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Nasal mucosal inhalation of amyloid-beta peptide 3-10 defective adenovirus attenuates cytotoxicity induced by beta-amyloid (1-42) 期刊论文
NEURAL REGENERATION RESEARCH, 2014, 卷号: 9, 期号: 8, 页码: 872-877
作者:  Jiang Tongzi;  Guo Wanshu;  Sha Sha;  Xing Xiaona;  Guo Rong;  Cao Yunpeng
收藏  |  浏览/下载:140/0  |  提交时间:2021/02/02
ALZHEIMERS-DISEASE  TRANSGENIC MICE  TANDEM REPEATS  MOUSE MODEL  IMMUNIZATION  VACCINATION  MEMORY  IMMUNOTHERAPY  ANTIBODIES  DECLINE  nerve regeneration  neurodegenerative disease  Alzheimer's disease  immunotherapy  amyloid-beta peptide vaccine  cytokines  humoral immunity  inflammation  NSFC grant  neural regeneration  
Induced Th2 dominant immune response in APPswe, PSEN1dE9 transgenic mice after nasal immunization with an adenoviral vector encoding 10 tandem repeats of beta-amyloid 3-10 期刊论文
NEURAL REGENERATION RESEARCH, 2011, 卷号: 6, 期号: 26, 页码: 2005-2012
作者:  Guo Rong;  Huang Kui;  Jiang Tongzi;  Li Jian;  Li Yu;  Xing Xiaona;  Cao Yunpeng
收藏  |  浏览/下载:114/0  |  提交时间:2021/02/26
ALZHEIMERS-DISEASE  MOUSE MODEL  FOLLOW-UP  PEPTIDE  NEUROPATHOLOGY  A-BETA-1-40/42  VACCINATION  IMMUNOGENS  PATHOLOGY  PROTEIN  Alzheimer's disease  immunotherapy  gene vaccine  amyloid plaque  T cell immunity response  neural regeneration  
Ureido-modification of the resin-bound LHRH analogue with N,N '-carbonyldiimidazole 期刊论文
CHINESE CHEMICAL LETTERS, 2009, 卷号: 20, 期号: 6, 页码: 668-671
作者:  Gao Yong Qing;  Zhou Ning;  Lv Yu Jian;  Cheng Mao Sheng;  Liu Ke Liang
收藏  |  浏览/下载:109/0  |  提交时间:2021/02/02
UREAS  Urea moiety  N,N'-carbonyldiimidazole (CDI)  Solid-phase  Peptide  
Protective effect of ghrelin on left ventricular remodeling in spontaneously hypertensive rats is associated with the peroxisome proliferator-activated receptor gamma-dependent pathway 期刊论文
CHINESE MEDICAL JOURNAL, 2008, 卷号: 121, 期号: 22, 页码: 2299-2304
作者:  Li Zhao;  Zhu Xiaoying;  Li Meng;  Bai Yinglong;  Hu Jian
收藏  |  浏览/下载:86/0  |  提交时间:2021/02/02
HEART-FAILURE  MACROPHAGES  DYSFUNCTION  MYOCARDIUM  CACHEXIA  PEPTIDE  ALPHA  ACID  ghrelin  hypertension  collagen  peroxisome proliferator-activated receptor gamma  left ventricular remodeling  
Cyclophilin A affects Bcl-2 and Bax expression following beta-amyloid fragment 25-35-induced injury to PC12 cells 期刊论文
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 6, 页码: 585-588
作者:  Cheng Li;  Zhang Chaodong
收藏  |  浏览/下载:85/0  |  提交时间:2021/02/02
IN-VITRO  APOPTOSIS  PEPTIDE  MITOCHONDRIAL  INHIBITION  MELATONIN  NEURONS  DEATH  cyclophilin A  pheochromocytoma (PC12) cells  beta-amyloid fragment 25-35  Bcl-2  Bax  
Cyclophilin A affects Bcl-2 and Bax expression following beta-amyloid fragment 25-35-induced injury to PC12 cells 期刊论文
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 6, 页码: 585-588
作者:  Cheng Li;  Zhang Chaodong
收藏  |  浏览/下载:93/0  |  提交时间:2021/02/02
IN-VITRO  APOPTOSIS  PEPTIDE  MITOCHONDRIAL  INHIBITION  MELATONIN  NEURONS  DEATH  cyclophilin A  pheochromocytoma (PC12) cells  beta-amyloid fragment 25-35  Bcl-2  Bax  
Template-assisted rational design of peptide inhibitors of furin using the lysine fragment of the mung bean trypsin inhibitor 期刊论文
FEBS JOURNAL, 2006, 卷号: 273, 期号: 17, 页码: 3907-3914
作者:  Tao, Hu;  Zhang, Zhen;  Shi, Jiahao;  Shao, Xiao-xia;  Cui, Dafu;  Chi, Cheng-Wu
收藏  |  浏览/下载:95/0  |  提交时间:2021/02/02
furin  kexin  molecular design  mung bean trypsin inhibitor  peptide synthesis  
Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and X-ray crystallography validation 期刊论文
PROTEIN SCIENCE, 2006, 卷号: 15, 期号: 9, 页码: 2071-2081
作者:  Cai, Jianhua;  Han, Cong;  Hu, Tiancen;  Zhang, Jian;  Wu, Dalei;  Wang, Fangdao;  Liu, Yunqing;  Ding, Jianping;  Chen, Kaixian;  Yue, Jianmin;  Shen, Xu;  Jiang, Hualiang
收藏  |  浏览/下载:88/0  |  提交时间:2021/02/02
peptide deformylase  protein crystallization  reverse docking  enzyme inhibitor  Helicobacter pylori  
Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and X-ray crystallography validation 期刊论文
PROTEIN SCIENCE, 2006, 卷号: 15, 期号: 9, 页码: 2071-2081
作者:  Cai, Jianhua;  Han, Cong;  Hu, Tiancen;  Zhang, Jian;  Wu, Dalei;  Wang, Fangdao;  Liu, Yunqing;  Ding, Jianping;  Chen, Kaixian;  Yue, Jianmin;  Shen, Xu;  Jiang, Hualiang
收藏  |  浏览/下载:100/0  |  提交时间:2021/02/02
peptide deformylase  protein crystallization  reverse docking  enzyme inhibitor  Helicobacter pylori  
Application of phage-displayed single chain antibodies in western blot 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2005, 卷号: 37, 期号: 3, 页码: 205-209
作者:  Ding YL;  Liu MY;  Han W;  Yang SL;  Liu H;  Gong Y
收藏  |  浏览/下载:97/0  |  提交时间:2021/02/02
B-LYMPHOCYTE STIMULATOR  FUSION PHAGE  TUMOR-CELLS  LIBRARY  ANTIGENS  PROTEIN  IDENTIFICATION  SELECTION  PEPTIDE  BLYS  phage-display  anitbody  Western blot