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Design, Synthesis and Antiproliferative Activity of Chrysin Derivatives Bearing Triazole Moieties 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 2, 页码: 440-446
Authors:  Luan Tian;  Quan Zheshan;  Fang Yingquan;  Yang Hongjing
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INHIBITION  CELLS  chrysin  synthesis  triazole  derivatives  antiproliferation  
Identification of hydrazone moiety-bearing aminopyrimidines as potent antitumor agents with selective inhibition of gefitinib-resistant H1975 cancer cells 期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 5, 页码: 991-994
Authors:  Qin MingZe;  Wang Lei;  Yan Shuang;  Ma JunJie;  Tian Ye;  Zhao YanFang;  Gong Ping
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TYROSINE KINASE INHIBITOR  LUNG-CANCER  RECEPTOR  T790M  MUTANT  MUTATION  Aminopyrimidines  EGFR T790M/L858R  Selectivity  Anti-resistance  Antiproliferative activity  
Identification of hydrazone moiety-bearing aminopyrimidines as potent antitumor agents with selective inhibition of gefitinib-resistant H1975 cancer cells 期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 5, 页码: 991-994
Authors:  Qin MingZe;  Wang Lei;  Yan Shuang;  Ma JunJie;  Tian Ye;  Zhao YanFang;  Gong Ping
Favorite  |  View/Download:59/0  |  Submit date:2021/02/02
TYROSINE KINASE INHIBITOR  LUNG-CANCER  RECEPTOR  T790M  MUTANT  MUTATION  Aminopyrimidines  EGFR T790M/L858R  Selectivity  Anti-resistance  Antiproliferative activity  
Synthesis and antiproliferative activity of novel 4-substituted-phenoxy-benzamide derivatives 期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 10, 页码: 1307-1310
Authors:  Sun ChiYu;  Li YangSheng;  Shi AiLong;  Li YaFei;  Cao RuiFang;  Ding HuaiWei;  Yin QingQing;  Zhang LiJuan;  Zheng HuaChuan;  Song HongRui
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HEDGEHOG SIGNALING PATHWAY  BASAL-CELL CARCINOMA  INHIBITORS  DISCOVERY  DESIGN  ANTAGONISTS  IDENTIFICATION  VISMODEGIB  CANCER  POTENT  Aryl cycloaliphatic amine  Antiproliferative activity  Hedgehog signaling  
Synthesis and antiproliferative activity of novel 4-substituted-phenoxy-benzamide derivatives 期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 10, 页码: 1307-1310
Authors:  Sun ChiYu;  Li YangSheng;  Shi AiLong;  Li YaFei;  Cao RuiFang;  Ding HuaiWei;  Yin QingQing;  Zhang LiJuan;  Zheng HuaChuan;  Song HongRui
Favorite  |  View/Download:58/0  |  Submit date:2021/02/02
HEDGEHOG SIGNALING PATHWAY  BASAL-CELL CARCINOMA  INHIBITORS  DISCOVERY  DESIGN  ANTAGONISTS  IDENTIFICATION  VISMODEGIB  CANCER  POTENT  Aryl cycloaliphatic amine  Antiproliferative activity  Hedgehog signaling  
Synthesis, Crystal Structure and Antiproliferative Activity of Ethyl 1-(Phenylcarbamoyl)-2-3,4,5-trimethoxyphenyl)cyclopropanecarboxylae 期刊论文
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2014, 卷号: 33, 期号: 6, 页码: 876-880
Authors:  Zhang JingYi;  Zhong HanYu;  Shi GuoBing
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ANTITUMOR-ACTIVITY  DERIVATIVES  3,4,5-trimethoxyphenyl  synthesis  crystal structure  antiproliferative activities  
Synthesis, Crystal Structure and Antiproliferative Activity of Ethyl 1-(Phenylcarbamoyl)-2-3,4,5-trimethoxyphenyl)cyclopropanecarboxylae 期刊论文
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2014, 卷号: 33, 期号: 6, 页码: 876-880
Authors:  Zhang JingYi;  Zhong HanYu;  Shi GuoBing
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ANTITUMOR-ACTIVITY  DERIVATIVES  3,4,5-trimethoxyphenyl  synthesis  crystal structure  antiproliferative activities  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
Authors:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
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ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
Authors:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
Favorite  |  View/Download:42/0  |  Submit date:2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
Syntheses and Antiproliferative Activities of Novel Diarylthiosemicarbazide Derivatives 期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2013, 卷号: 29, 期号: 1, 页码: 62-66
Authors:  Zhai Xin;  He Ying;  Yang Zhen;  Gong Ping
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KINASE INHIBITORS  ANTITUMOR AGENTS  DESIGN  BENZIMIDAZOLES  CYTOTOXICITY  Thiosemicarbazide  N-methylpicolinamide  Antiproliferative activity