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Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents 期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372
作者:  Zhang Lan;  Deng Xinshan;  Wu Jiaofeng;  Meng Guangpeng;  Liu Congchong;  Chen Guzhou;  Zhao Qingchun;  Hu Chun
收藏  |  浏览/下载：148/0  |  提交时间：2021/02/02
MOLECULAR TARGETED DRUGS  TYROSINE KINASE  CANCER-CELLS  EGFR  RESISTANCE  POTENT  DISCOVERY  NSCLC  Anticancer activity  Epidemal growth factor receptor(EGFR) inhibitor  N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative  
Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents 期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372
作者:  Zhang Lan;  Deng Xinshan;  Wu Jiaofeng;  Meng Guangpeng;  Liu Congchong;  Chen Guzhou;  Zhao Qingchun;  Hu Chun
收藏  |  浏览/下载：142/0  |  提交时间：2021/02/02
MOLECULAR TARGETED DRUGS  TYROSINE KINASE  CANCER-CELLS  EGFR  RESISTANCE  POTENT  DISCOVERY  NSCLC  Anticancer activity  Epidemal growth factor receptor(EGFR) inhibitor  N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative  
Synthesis, Anticancer and Antibacterial Activities of Novel 2-Amino-4-phenylthiazole Derivatives Containing Amide Moiety 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 9, 页码: 2377-2384
作者:  Zhang Zhihua;  Chen Yu;  Chai Baoshan;  Yang Xiaoman;  Cai Xiaoyu;  Cui Bo;  You Song
收藏  |  浏览/下载：143/0  |  提交时间：2021/02/02
BIOLOGICAL EVALUATION  KINASE INHIBITORS  SORAFENIB ANALOGS  ANTITUMOR AGENTS  RATIONAL DESIGN  2-AMINOTHIAZOLES  BRAF  MELANOMA  THIOUREA  GROWTH  thiazole derivative  amide  synthesis  anticancer  antibacterial  
Identification of hydrazone moiety-bearing aminopyrimidines as potent antitumor agents with selective inhibition of gefitinib-resistant H1975 cancer cells 期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 5, 页码: 991-994
作者:  Qin MingZe;  Wang Lei;  Yan Shuang;  Ma JunJie;  Tian Ye;  Zhao YanFang;  Gong Ping
收藏  |  浏览/下载：156/0  |  提交时间：2021/02/02
TYROSINE KINASE INHIBITOR  LUNG-CANCER  RECEPTOR  T790M  MUTANT  MUTATION  Aminopyrimidines  EGFR T790M/L858R  Selectivity  Anti-resistance  Antiproliferative activity  
Identification of hydrazone moiety-bearing aminopyrimidines as potent antitumor agents with selective inhibition of gefitinib-resistant H1975 cancer cells 期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 5, 页码: 991-994
作者:  Qin MingZe;  Wang Lei;  Yan Shuang;  Ma JunJie;  Tian Ye;  Zhao YanFang;  Gong Ping
收藏  |  浏览/下载：138/0  |  提交时间：2021/02/02
TYROSINE KINASE INHIBITOR  LUNG-CANCER  RECEPTOR  T790M  MUTANT  MUTATION  Aminopyrimidines  EGFR T790M/L858R  Selectivity  Anti-resistance  Antiproliferative activity  
Biodegradable magnesium wire promotes regeneration of compressed sciatic nerves 期刊论文
NEURAL REGENERATION RESEARCH, 2016, 卷号: 11, 期号: 12, 页码: 2012-2017
作者:  Li, Bo-han;  Yang, Ke;  Wang, Xiao
收藏  |  浏览/下载：131/0  |  提交时间：2021/02/02
nerve regeneration  peripheral nerve regeneration  biodegradable  magnesium wire  sciatic nerve  rats  nerve growth factor  P75 neurotrophin receptor  tyrosine receptor kinase A  neural regeneration  
Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707
作者:  Liu Tongchao;  Peng Xia;  Ma Yuchi;  Ji Yinchun;  Chen Danqi;  Zheng Mingyue;  Zhao Dongmei;  Cheng Maosheng;  Geng Meiyu;  Shen Jingkang;  Ai Jing;  Xiong Bing
收藏  |  浏览/下载：156/0  |  提交时间：2021/02/02
RECEPTOR TYROSINE KINASE  INVASIVE GROWTH  SCATTER FACTOR  CANCER  DOCKING  c-Met inhibitors  hepatocyte growth factor receptor  imidazo1,2-apyridine  anticancer agents  drug discovery  
Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707
作者:  Liu Tongchao;  Peng Xia;  Ma Yuchi;  Ji Yinchun;  Chen Danqi;  Zheng Mingyue;  Zhao Dongmei;  Cheng Maosheng;  Geng Meiyu;  Shen Jingkang;  Ai Jing;  Xiong Bing
收藏  |  浏览/下载：132/0  |  提交时间：2021/02/02
RECEPTOR TYROSINE KINASE  INVASIVE GROWTH  SCATTER FACTOR  CANCER  DOCKING  c-Met inhibitors  hepatocyte growth factor receptor  imidazo1,2-apyridine  anticancer agents  drug discovery  
Study of spatial signal transduction in bistable switches 期刊论文
FRONTIERS OF PHYSICS, 2016, 卷号: 11, 期号: 5
作者:  Zhao Qi;  Yao ChengGui;  Tang Jun;  Liu LiWei
收藏  |  浏览/下载：103/0  |  提交时间：2021/02/02
PROTEIN-KINASE CASCADES  POSITIVE-FEEDBACK  NEGATIVE FEEDBACK  CELL POLARITY  BISTABILITY  GRADIENTS  ULTRASENSITIVITY  OSCILLATIONS  ACTIVATION  OOCYTES  signal processing  reaction-diffusion model  nonlinear dynamics  spatial switch  
Study of spatial signal transduction in bistable switches 期刊论文
FRONTIERS OF PHYSICS, 2016, 卷号: 11, 期号: 5
作者:  Zhao Qi;  Yao ChengGui;  Tang Jun;  Liu LiWei
收藏  |  浏览/下载：108/0  |  提交时间：2021/02/02
PROTEIN-KINASE CASCADES  POSITIVE-FEEDBACK  NEGATIVE FEEDBACK  CELL POLARITY  BISTABILITY  GRADIENTS  ULTRASENSITIVITY  OSCILLATIONS  ACTIVATION  OOCYTES  signal processing  reaction-diffusion model  nonlinear dynamics  spatial switch